The observational epidemiology Southern California Children's Health Study (CHS) and the experimental UCLA Challenge Study together offer a unique opportunity to investigate the interactions between genetic variation and exposure to particulates on the risk of asthma through joint modeling of effects ...
participants in CHARLS 2011–2012 and NHANES 1999–2018. CHARLS: China Health and Retirement Longitudinal Study; CI: confidence interval; HDL: high-density lipoprotein; NHANES: National Health and Nutrition Examination Survey; OR: odds ratios; PIR: poverty income ratio; Q2: second quartile; Q3: ...
The study follows the Transparent Reporting of Evaluations with Nonrandomized Designs (TREND) reporting guideline for nonrandomized controlled trials. The trial protocol appears in Supplement 1. The study design is summarized in Figure 1. After informed consent, parents of children aged ...
Department of Oral Epidemiology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan Mariko Naito Center for Public Health Sciences, National Cancer Center, Tokyo, Japan Shoichiro Tsugane Division of Molecular Pathology, Institute of Medical Science, The University of...
due to regional differences in the epidemiology of MAFLD, the predictive effectiveness of various indexes across different populations varies. Additionally, there are few studies examining the comprehensive use of these indexes for predicting MAFLD in China. Therefore, further comprehensive evaluations and ...
Accordingly, characterizing microbial biomarkers from microbiota profiles has great potential for translational and precision medicine.6 The gut microbiome has been extensively studied over the past years with regards to obesity, while many works have only considered BMI classes in their study designs for...
There is a need to further investigate the PICO framework in a larger study to determine whether it can be well represented in the titles of different research designs. That, in turn, will help the precision of searches performed on a PICO-formatted screen to receive relevant citations. 展开...
and target genes35. It designs a diagram demonstrating the association of TFs, protein complexes, and protein kinases, which are responsible for the changes in the expression level of common up- and downregulated genes and transcriptome35. The inferred network of regulatory factors was downloaded and...
adapted an age-period-cohort modeling approach to estimate breast cancer incidence in the absence of screening among the overall and Black female population21,22; model M used Surveillance, Epidemiology, and End Results (SEER) rates with a linear model based on rates in 1975 and calibrated over...
2015, Journal of Clinical Epidemiology Citation Excerpt : Modern clinical and epidemiological studies increasingly rely on longitudinal designs with repeated measurements of prognostic and risk factors during the follow-up, which imply more complex data structures. In the past decade, many studies have ...