Diabetes mellitus is a well-known risk factor for cardiovascular disease, and brings an increased risk of vascular events and a higher mortality rate. Treatment guidelines recommend statins in patients with diabetes, with low-density lipoprotein cholesterol (LDL-C) targets of 100 mg dl−1 (∼...
cholesterol总胆固醇HDL - CHigh-density lipoprotein cholesterol高密度脂蛋白胆固醇LDL - CLow-density lipoprotein cholesterol低密度脂蛋白胆固醇apoA1Apolipoprotein A1载脂蛋白A1apoBApolipoprotein B载脂蛋白BLpaLipoprotein A脂蛋白A论文独创性说明本人申明所呈交的学位论文是在我个人在导师的指导下进行的研究 工作及...
Ito MK, Nanchen D, Rodondi N, Paccaud F, Waeber G, Vollenweider P, et al. Statins for cardiovascular prevention according to different strategies: a cost analysis. Am J Cardiovasc Drugs 2011;11(1):33--44.Ito MK, Nanchen D, Rodondi N, Paccaud F, Waeber G, Vollenweider P, et al...
(P0.05)and the levels of ALT,BG,SCr and CK were not significantly different before and after treatment in three groups(P0.05).No patients had myalgia,death,re-infarction and PCI again in one month after PCI in three groups.Conclusion The treatment with different statins is effective and safe...
There were no significant differences in the rate of medication with other than statins for patients between the two groups (28.6% (LBHs) vs. 14.4% (HBHs); P = 0.028). Interestingly, no differences in echocardiographic parameters were observed between the LBHs and HBHs. Clinical course ...
A meta-analysis of the effects of statins on serum C-reactive protein in Chinese population with coronary heart disease or hyperlipidemia There is little doubt that statins reduce cardiovascular events more than what the lipid lowering effect can account for. Additional mechanisms have been p... PP...
What Makes CAD Different for Women? Hormonal changes.Before you start menopause, the hormone estrogen helps protect you from getting coronary artery disease. That’s because estrogen boosts your “good” (HDL) cholesterol. It also helps yourarteriesstay flexible, so they can widen to carry more ...
The recognition that dyslipidaemia is one of the most critical risk factors for cardiovascular disease has caused researchers to tightly focus on the lowering of cholesterol (LDL-C) in both primary and secondary prevention, by inhibiting formation, increased uptake or reduced resorption [3]. In ...
Age, gender, systolic blood pressure, total & HDL cholesterol, smoking status and treatment for hypertension were considered in FRS-CHD risk score calculation. Diabetes was considered as a CVD equivalent. In FRS-CVD, diabetes was considered as a risk factor for score calculation. In ASCVD calcula...
In adults, this mechanism is believed to be responsible for elimination of 1–2 mg of cholesterol per 24 h. The details of this particular mechanism for sterol transport are, however, not known. More recently we described a second mechanism for the elimination of brain cholesterol conversion ...