Background Although rituximab in the combination of CHOP chemotherapy has been widely used as the standard treatment for several kinds of B-cell non-Hodgkin lymphoma (B-NHL), a great number of B-NHL patients treated with this immunotherapy still develop primary and secondary resistance. Recently ...
Let’s try an analogy. Consider the hair loss of a cancer patient. Doctors make a choice, weighing the harms of chemotherapy with the risks of nontreatment. When doctors choose to apply chemotherapy, they “cause” the loss of hair and other toxic side effects of chemotherapy. The choice t...
The term “Cervical cancer” is characterized by an abrupt and unusual growth of cells in the cervical lining. The cause of this disease is the human papillomavirus (HPV) attack on the body and the medium of transmission is sexual intercourse. This abnormal cell growth is called dysplasia or ...
Twelve of them showed liver metastases, whereas 13 had previously under- gone surgery and six had previously received a 5-fluorouracil based line of chemotherapy. Other characteristics are shown in Table 1. No patients with a pathological diagnosis of anaplastic malignancy, well-differentiated ...
These findings suggest that iron oxide-CMCH-genistein nano-formulation can be a multifunctional drug delivery platform for combination therapy and chemotherapy [92]. Genistein is also an epigenetic modulator. Polycomb protein seems to be involved in epigenetic repression of the oral squamous cell ...
This leads to the inhibition of ALOX15 and a reduction in lipid ROS accumulation in cancer cells, ultimately leading to a reduction in chemotherapy sensitivity [118]. Similarly, in 2021, the same team discovered that exosomal lncFERO (exo-lncFERO) secreted by gastric cancer cells could regulate...
Chemotherapy.Exposure toradiationcan have an effect. Certain medications.These includesteroids,such ashydrocortisoneorprednisone,and anti-seizuredrugs, such ascarbamazepine(Carbatrol,Tegretol),gabapentin(Gralise,Horizant,Neurontin), orphenytoin(Dilantin,Phenytek). ...
What are the effects of different soft tissue tumors as an insult to the body? Why is Taxol used to treat certain kinds of cancer but not all? Explain how are drugs used to target tumor cells during chemotherapy? Define a cancer cluster. What are some of the characteristics you would look...
Active NFκB is linked to poor prognosis, low survival rate, and metastasis in cancer patients [42]. NFκB regulates various genes involved in cancer cells’ survival, invasion, and angiogenesis [42]. Constitutive expression of NFκB in cancer cells results in resistance to chemotherapy-induced ...
strategies are currently adopted for breast cancer, including the removal of tumors and their adjacent lymph nodes by surgical resection17, chemotherapy18, radiotherapy (which is typically associated with numerous complications)19, and immunotherapy. Chemotherapy agents such as Ribociclib, a cyclin-...