Autoimmune diseases are developed when the immune system mistakenly attacks the body's cells. These inflammatory disorders can be inherited or triggered by external forces, such as type 1 diabetes, which is caused by the immune system's destruction of pancreatic beta cells. So far, stem cells ...
IgM antibodies against phosphorylcholine (anti-PC) and malondialdehyde (anti-MDA) may have protective properties in cardiovascular and rheumatic diseases. We here compare these antibodies in systemic rheumatic conditions and study their properties. Anti-PC and anti-MDA was measured using ELISA in patient...
Antivirulence drugs have been approved by the US Food and Drug Administration for bacterial toxin-mediated diseases, and investigational drugs for antibiotic-resistant bacteria have entered clinical trials. Several others are in preclinical development. Antivirulence drugs are likely to have distinct properti...
Effects of low-dose-gamma rays on the immune system of different animal models of disease 来自 mendeley.com 喜欢 0 阅读量: 43 作者:N Shimura,S Kojima 摘要: We reviewed the beneficial or harmful effects of low-dose ionizing radiation on several diseases based on a search of the literature....
Altered regu- lation of cell death or activation and expansion of immune cells disrupts homeostasis of the immune system, which may result in potentially lethal inflammatory diseases. A subfamily of proteins that contribute to immune homeostasis possesses a hexahelical bundle motif, called the death ...
Since autophagy exerts essential functions in degrading superfluous proteins and organelles, the role of autophagy in the physio-pathologic process of many diseases have been investigated. Until now, alternative autophagy has been emerging to be closely related to different diseases, such as ...
D Raphael - 《Clinical Infectious Diseases An Official Publication of the Infectious Diseases Society of America》 被引量: 6发表: 2011年 PB2280: COVID-19 INFECTION IN PATIENTS WITH ACUTE LEUKEMIA Background: Background: Due to disorders in the immune system associated with the manifestations of ...
P Henry - 《Journal of Infectious Diseases》 被引量: 7发表: 1929年 Brain transcriptomics reveal the activation of neuroinflammation pathways during acute Orientia tsutsugamushi infection in mice Scrub typhus, an acute febrile illness caused by Orientia tsutsugamushi (Ot), is prevalent in endemic area...
immune system function, where a significant decline usually means serious diseases and unfavorable prognosis11. NK cells are the first line of immunity defense for tumor cells; they can nonspecifically identify and eliminate tumor cells; and inhibit tumor formation, growth, spread and metastasis12, ...
but still depend on oncogenic JAK2–STAT signaling8,9,10. However, it is unclear how the same mutation or oncogenic pathway can give rise to different diseases with variable progression (with PV showing a higher transformation risk into secondary myelofibrosis or leukemia, compared with ET)11,12...