Charlier, "Calcu- lated radiosensitivities of different forms of DNA in solution," Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, vol. 105, no. 1-4, pp. 328-331, 1995.V. Michalik, M. Spotheim-Maurizot, M. Charlier, Calculated ...
The structure consists of major and minor grooves that show little difference in width, unlike that of A-DNA and B-DNA. The width of the helix in Z-DNA is 1.8nm, which is narrower than other forms of DNA. Z-DNA is inherently unstable. It appears as a transient structure o...
Whole-genome sequencing (WGS) and whole-exome sequencing (WES) provide the sequence of DNA bases across the genome and exome, respectively. Whole-transcriptome sequencing provides sequence information about coding and multiple noncoding forms of RNA to assess variations and ...
forms of RNA to assess variations and gene expression levels across the entire transcriptome. Targeted sequencing covers a relatively small set of genes or targeted regions of interest. The fast turnaround time, low cost, low sample input requirement, and relative ease ...
Drugs(药物) come in different forms.However,can you imagine that drugs come in eggs?A team of scientists from England prove that it can come true.They have developed special chickens that lay the eggs with drugs inside.These special drugs can help treat some kinds of diseases.Until now,they...
aIf the DNA sequence at a locus varies between individuals, the different forms of this sequence are called alleles. 如果脱氧核糖核酸序列在所在地变化在个体之间,这个序列的不同的形式称等位基因。[translate]
Altered forms of DNA that occur as the result of exposure to carcinogens (in the case of smokers these would be the carcinogens present in cigarette smoke). A DNA adduct may have several possible outcomes: it may lead to cell death by apoptosis; it may be repaired, resulting in a return...
Drugs(药物) come in different forms. However, can you imagine that drug come in chicken eggs? A team of scientists from England prove that it can come true. They have developed special chickens that lay eggs with drugs inside. These special drugs can help treat some kinds of diseases. Unti...
The dynamics of DNA in the cell nucleus plays a role in cellular processes and fates but the interplay of DNA mobility with the hierarchical levels of DNA
Loss of functional β-cell mass is the key mechanism leading to the two main forms of diabetes mellitus — type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM). Understanding the mechanisms behind β-cell failure is critical to prevent or revert disease. Basic pathogenic differen...