Why do different forms of DNA exist? There is simply not enough room for the DNA to be stretched out in a perfect, linear B-DNA conformation. In nearly all cells, from simple bacteria through complex eukaryotes, the DNA must be compacted by more than a thousand fold in order even to fi...
Michalik V, Spothelm-Maurizot M, Charlier M (1995) Calculated radiosensitivities of different forms of DNA in solution Nucl Instr Met. Phys Res B 105, 328-331V. Michalik, M. Spotheim-Maurizot, and M. Charlier, "Calcu- lated radiosensitivities of different forms of DNA in solution," ...
The structure consists of major and minor grooves that show little difference in width, unlike that of A-DNA and B-DNA. The width of the helix in Z-DNA is 1.8nm, which is narrower than other forms of DNA. Z-DNA is inherently unstable. It appears as a transient structure ...
aIf the DNA sequence at a locus varies between individuals, the different forms of this sequence are called alleles. 如果脱氧核糖核酸序列在所在地变化在个体之间,这个序列的不同的形式称等位基因。[translate]
Postchallenge enzyme-linked immunospot values for Gag and Env as well as gag-specific T-helper responses correlated with control of viremia. Our data show that the combinations of DNA vaccines producing native and modified forms of antigens elicit more balanced immune responses able to significantly...
Despite the frequent use of ionising radiation (IR) in therapy and diagnostics and the unavoidable exposure to external radiation sources, our knowledge regarding the radiosensitivity of human blood cell populations is limited and published data, obtaine
Oligomeric forms of A尾 peptides are implicated in Alzheimer's disease (AD) and disrupt membrane integrity, leading to cytosolic calcium (Ca(2+)) elevation... A Demuro,M Smith,I Parker - 《Journal of Cell Biology》 被引量: 231发表: 2011年 ...
Drugs(药物) come in different forms.However,can you imagine that drugs come in eggs?A team of scientists from England prove that it can come true.They have developed special chickens that lay the eggs with drugs inside.These special drugs can help treat some kinds of diseases.Until now,they...
In conclusion, carboplatin forms the same bifunctional adducts as cisplatin.TRUNCATED AT 250 WORDS) 展开 关键词: Cancer-patients Cyto-toxicity Cisplatin Cis-diamminedichloroplatinum(ii Pharmacokinetics Chemotherapy Feasibility Induction Binding DOI: 10.1021/bi00026a031 被引量: 244 ...
The dynamics of DNA in the cell nucleus plays a role in cellular processes and fates but the interplay of DNA mobility with the hierarchical levels of DNA