The present invention provides methods for diagnosing mental disorders. The invention also provides methods of identifying modulators of mental disorders as well as methods of using these modulators to treat patients suffering from mental disorders.Juan F. LopezRobert C. Thompson...
1. The efficacies of different classes of antidepressants were investigated using the forced swimming test with mice at different ages. 2. Imipramine (4-32 mg/kg), desipramine (2-16 mg/kg) and bupropion (32, 64 mg/kg) showed activity in all age groups. 3. The selective serotonin reupta...
Two subclasses of cells in the simple family have been recognized: ordinary simple and fast simple cells. Two cell classes (A-cells and silent periodic ... JJ Kulikowski,PO Bishop,H Kato - 《Experimental Brain Research》 被引量: 138发表: 1981年 Characterization of gene expression profiles for...
In each case, the total risk of potential fatal ventricular tachycardia is low [9]. Several factors can cause QT prolongation in patients with cancer [11], [12]: Therefore, it is mandatory that patient care is improved by knowledge of the different classes of anti-cancer drugs associated ...
This group of medications is divided into two classes: typical and atypical antipsychotic medications. Typical antipsychotics tend to more strongly block dopamine. Atypical antipsychotics have greater effects on serotonin. Both groups of antipsychotics share similar side effects, such as dry mouth, ...
Background: The use of antidepressants and benzodiazepines is increasing in Australia and worldwide, and it is thought that some of the prescribing of these classes of drugs may be inappropriate. However, the demographic characteristics of the subgroups of the population responsible for this increase...
Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus The present study demonstrates that chronic, but not acute, adminstration of several different classes of antidepressants, including serotonin- and norepin... M Nibuya,Nestler...
.Most studies that compare the antidepressant efficacy of the newer generation of selective serotonin reuptake inhibitors (SSRIs) and moclobemide (reversible inhibitor of monoamine oxidase A) with the older tricyclic antidepressants (TCAs) indicate no difference between these classes of drugs in severe...
Combining pharmacological agents across different neurotransmitter systems increases heterogeneity among studies; however multiple neurotransmitter systems are involved in cognitive dysfunction in schizophrenia and all these different classes of drugs have the same aim (i.e., to improve cognition). Therefore,...
学术范收录的Journal Fast and simple procedure for liquid–liquid extraction of 136 analytes from different drug classes for development of a liquid chromatographic-tandem mass spectrometric quantification method in human blood plasma,目前已有全文资源,