CM contractility depends not only on the myofilaments properties, but also on the diastolic and systolic C a2+levels. The smaller contraction Table 1 Intracellular Ca2+ handling properties in female cardiomyocytes compared to male cardiomyocytes Parameters Differences Species Source Age [...
The rise in intracellular Ca2+concentration caused by the Ca2+transients allows Ca2+to bind to the myofilaments, specifically troponin C, ultimately resulting in contraction of the myocyte [4,35]. Relaxation occurs when the majority of Ca2+is sequestered into the SR via the sarco/endoplasmic ret...
Differences in gene expression by sex have been observed in human brain across the major developmental stages (prenatal, early childhood, puberty and adulthood)9and in splicing10. Reasons for sex-biased gene expression for some autosomal genes may be related to the presence of androgen or estrogen...
These two types are known to vary in resistance to Daphnia magna grazing: thin filaments (2.5 m). In this study, we investigated whether the difference in the vulnerability to grazing of thin and thick filaments is a result of different thickness of their cell walls, a ...
(actin filament) muscle Z-line, alpha 2; 13, Capping protein (actin filament) muscle Z-line, beta isoform a; 14, Cathepsin D precursor; 15, Chaperonin subunit 2 (beta); 16, Chia protein; 17, Chitinase 3-like 3 precursor; 18, Chitinase-related protein MCRP; 19, Chloride intracellular ...
Mechanical thresholds in the vibrissal pad were determined using von Frey filaments as previously described by us27,36. Briefly, animals were first acclimatized to von Frey filaments a day prior to experimentation by exposing the animals to the lowest force of the filament. Following this, mechanic...
Mechanical thresholds in the vibrissal pad were determined using von Frey filaments as previously described by us27,36. Briefly, animals were first acclimatized to von Frey filaments a day prior to experimentation by exposing the animals to the lowest force of the filament. Following this, mechanic...
(actin filament) muscle Z-line, alpha 2; 13, Capping protein (actin filament) muscle Z-line, beta isoform a; 14, Cathepsin D precursor; 15, Chaperonin subunit 2 (beta); 16, Chia protein; 17, Chitinase 3-like 3 precursor; 18, Chitinase-related protein MCRP; 19, Chloride intracellular ...
Recombination, the process of DNA exchange between homologous chromosomes during meiosis, plays a major role in genomic diversity and evolutionary change. Variation in recombination rate is widespread despite recombination often being essential for progr
What structural features do epithelia that provide for protection have in common? What are the six classes of nutrients? Explain the primary functions of each of them. Describe and diagram the structure of a sarcomere and the primary component(s) of the thick and thin fi...