This chapter discusses a study to examine the differences in energy metabolism between neurons and glial cells in primary cultures. The cultures of isolated neurons and glial cells were prepared from brains of
Having verified the validity of our lifetime measurements, we then studied the distribution of our results, first focusing on the lifetimes of proteins from the mouse cortex, which spread from ~1 day to several hundred days, albeit most were between 3 and 13 days (Fig.2and Supplementary Da...
Moreover, sex differences were detected regarding the identity of Cyp19a1+ cells. Conclusions Females show overall a lower number of cells expressing Cyp19a1 in the limbic brain. In both sexes, aromatase is expressed in a region-specific manner in GABAergic and glutamatergic neurons. These ...
Glial density was not different between the sexes, but the total number of glial cells was higher in males than in females. These results demonstrate that the binocular visual cortex of the rat is sexually dimorphic in its volume and much of the difference is due to sex differences in the ...
A lot less is known about the two other isoforms of PANX1, namely PANX2 and PANX3, which have tissue-specific expression patterns. PANX2 is primarily expressed in neurons and glial cells and is involved in cellular differentiation16. Recent structural studies of PANX2 have further highlighted...
Transcriptional differences between normal and glioma- derived glial progenitor cells identify a core set of dysregulated genes. Cell Rep. 3, 2127-2141.Auvergne RM, Sim FJ, Wang S, Chandler-Militello D, Burch J, Al Fanek Y, Davis D, Benraiss A, Walter K, Achanta P, Johnson M, ...
Glial-like cells (GaMg glioma and CCF-STTG1 astrocytoma cell lines) displayed more pronounced drug-induced SREBP activation compared to the response in HCN2 human cortical neurons and SH-SY5Y neuroblastoma cells, indicating that antipsychotic-induced activation of lipogenesis is most prominent in ...
Supporting this idea, women between 18 and 44 years old have a higher survival rate than men of the same age or older women (over 50 years old) [6]. Interestingly, women have a greater risk of develop tumors in proximal colon than men. Also, the incidence of CRC in proximal colon ...
Sex differences in nuclear transcriptomes were observed for multiple different cell types including several different types of glutamate and GABAergic neurons, microglia, radial glia, and oligodendrocytes. Sex differences in the proportion of multiple different types of glutamate neurons, one type of GABA...
Therefore, the current study identified the differences in tongue-innervating sensory neurons between males and females under naïve and diseased state. We used tongue cancer as our disease model as approximately 50% of oral cancer patients report pain throughout the course of the disease and of ...