Ethanol metabolism is non-linear and the optimal values of Vmax (2.45 millimoles/min/70 kg) and Km (0.096 millimole/liter) were chosen using the non-linear Powell [20] minimization routine that is built into PKQuest. This feature of PKQuest allows the user to minimize the error between ...
Ethanol metabolism is non-linear and the optimal values of Vmax (2.45 millimoles/min/70 kg) and Km (0.096 millimole/liter) were chosen using the non-linear Powell [20] minimization routine that is built into PKQuest. This feature of PKQuest allows the user to minimize the error between ...