The communication between cancer cells and the environment is a prerequisite for generating a favorable tumor microenvironment, and it is mediated by soluble molecules such as cytokines, growth factors, and extracellular vesicles. Mounting evidence suggests that cytokines play a decisive role in CRC ...
Because so many components of the live attenuated mycobacteria, irrespective of the strain, are able to activate the robust immune cascade that ultimately results in tumour-cell killing, it is unlikely that variabilities between strains play a major role [27,29]. However, not only the ...