我们提出了DIFFDOCK-PP,一种用于刚性蛋白质-蛋白质对接的扩散生成模型。我们的方法受到了分子对接领域最新进展的启发(Corso等,2022年),该方法通过生成模型来处理配体姿态的对接问题。DIFFDOCK-PP在性能上优于现有的深度学习模型,并与基于搜索的方法在计算成本的分数上表现竞争力。我们简单的方法的有效性为进一步研究利用...
For other interactions we recommend looking at [DiffDock-PP](https://github.com/ketatam/DiffDock-PP) (rigid protein-protein interactions), [AlphaFold-Multimer](https://github.com/google-deepmind/alphafold) (flexible protein-protein interactions) or [RoseTTAFold2NA](https://github.com/uw-ipd/...
[DiffDock-PP](https://github.com/ketatam/DiffDock-PP) (rigid protein-protein interactions), [AlphaFold-Multimer](https://github.com/google-deepmind/alphafold) (flexible protein-protein interactions) or [RoseTTAFold2NA](https://github.com/uw-ipd/RoseTTAFold2NA) (protein-nucleic acid interactions...
For other interactions we recommend looking at [DiffDock-PP](https://github.com/ketatam/DiffDock-PP) (rigid protein-protein interactions), [AlphaFold-Multimer](https://github.com/google-deepmind/alphafold) (flexible protein-protein interactions) or [RoseTTAFold2NA](https://github.com/uw-ipd/...
[DiffDock-PP](https://github.com/ketatam/DiffDock-PP) (rigid protein-protein interactions), [AlphaFold-Multimer](https://github.com/google-deepmind/alphafold) (flexible protein-protein interactions) or [RoseTTAFold2NA](https://github.com/uw-ipd/RoseTTAFold2NA) (protein-nucleic acid interactions...
[DiffDock-PP](https://github.com/ketatam/DiffDock-PP) (rigid protein-protein interactions), [AlphaFold-Multimer](https://github.com/google-deepmind/alphafold) (flexible protein-protein interactions) or [RoseTTAFold2NA](https://github.com/uw-ipd/RoseTTAFold2NA) (protein-nucleic acid interactions...
[DiffDock-PP](https://github.com/ketatam/DiffDock-PP) (rigid protein-protein interactions), [AlphaFold-Multimer](https://github.com/google-deepmind/alphafold) (flexible protein-protein interactions) or [RoseTTAFold2NA](https://github.com/uw-ipd/RoseTTAFold2NA) (protein-nucleic acid interactions...
[DiffDock-PP](https://github.com/ketatam/DiffDock-PP) (rigid protein-protein interactions), [AlphaFold-Multimer](https://github.com/google-deepmind/alphafold) (flexible protein-protein interactions) or [RoseTTAFold2NA](https://github.com/uw-ipd/RoseTTAFold2NA) (protein-nucleic acid interactions...