As simple as it seems, such a diff is not so trivial for an algorithm. Proposed solution Convert each config to ann-ary tree Do a deep comparison of then-ary trees Then-ary tree data structure will help: to represent how nested the items are, to do the match between blocks. ...
Dynamic reorganizations of TADs between health and disease states are associated with essential genome functions. However, computational methods for identifying reorganized TADs are still in the early stages of development. Here, we present DiffDomain, an algorithm leveraging high-dimensional random matrix...