Its chemistry is governed by the unshared electron pair on the nitrogen, thus it tends to react with acids to form salts. View all 2.12 Color/Form Clear colorless 2.13 Corrosivity Liquid diethylamine; will attack some forms of plastics, rubber, and coatings. 2.14 Decomposition When heated to...
At physiological pH mechlorethamine is readily and unimolecularly converted by way of the free base to a relatively stable aziridinium ion, which in turn reacts biomolecularly with available nucleophilic centers. In vivo alkylation of guanine occurs mainly at the position 7. The drug is ...