Glucose-lowering agents such as metformin, sodium-glucose co-transporter-2 (SGLT2) inhibitors and glucagon-like peptide 1 (GLP-1) receptor agonists, are generally recommended to ameliorate hyperglycemia [4]. However, these drugs may initially exacerbate DR and have been frequently associated with ge...
In patients with type 2 diabetes, but not type 1 diabetes, abnormal secretion of incretins in response to oral nutrients has been described. In healthy youths, we recently reported accentuated glucagon-like peptide 1 (GLP-1) secretion in response to a diet soda sweetened with sucralose and ace...
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HFD小鼠模型表明, 睾丸中TNF-α, MCP-1和F4/80的mRNA表达水平增加, 而GLP-1受体(glucagon like peptide-1 receptor, GLP-1R)激动剂可通过减少促炎细胞因子的表达来改善精子质量[91]. 此外, 白色脂肪细胞产生的炎性细胞因子, 如TNF-α, IL-1和IL-6, 可能通过多种机制直接影响精子发生, 包括破坏支持细胞...
However, the utility of GLP-1 and PYY in predicting appetite response during dietary interventions remains unsubstantiated. This study investigated whether the decrease in hunger observed following low energy diet (LED)-induced weight loss was associated with increased circulating 'satiety pep...
However, it is still unclear whether GLP-1 or its analogs have any effects on the lipidome of adipose tissues. Beinaglutide (BN) is a recombinant human GLP-1 (rhGLP-1) that shares almost 100% homology with human GLP-1 (7–36). It is recommended for the treatment of T2DM by the ...
Evidence indicates that soluble fibers influence the production of glucagon-like peptide-1 (GLP-1), can delay gastric emptying, reduce glucose entry into the bloodstream, and thus modulate its absorption [65, 66]. The second mechanism is maintaining a healthy weight provided by a sustainable diet...
medications (e.g., metformin, acarbose, GLP-1 agonists, etc.) known to affect glucose homeostasis. All participants gave their informed consent before they participated in the study. The study was conducted in accordance with the Declaration of Helsinki, and the protocol was approved by the ...
The changes in the body weight of each group of mice are shown in Figure 1C. Before and after the intervention, the growth status of each group of mice was well. The body weight of the NC mice remained stable at 41 g, while that of the mice fed with a high-fat diet in each grou...
In addition to the standard WeightWatchers weight loss membership option, the company also provides two other support options: one for members living with diabetes and one for members on GLP-1 weight loss medications. The diabetes-tailored plan is specifically geared toward people who have been dia...