Exercise is known to improve hepatic mitochondrial health and mitophagy thus mitophagy may be a mediator in the treatment of obesity induced-NAFLD. PURPOSE The purpose of the study was to examine how weight loss from diet or diet combined with physical activity impacts hepatic mitochondrial content,...
Mitochondrial dysfunction may play an important role in the pathogenesis of ALS, which makes it a potential novel therapeutic target of intervention for ALS. Kong showed that KD can increase antioxidant power and attenuate oxidative stress in spinal cord injury by suppressing class I histone deacetylas...
-induced adduct formation in nuclear and mitochondrial DNA appear as early lesions in and are discussed in relation to apoptotic events in the progression ... N Jagadeesan,S Susanne,F Norbert,... - 《Carcinogenesis》 被引量: 154发表: 2005年 Relationships between DNA adduct formation and carcin...
2,3,4. Ongoing colony losses of the Western honey bee (Apis mellifera), a model species and key pollinator in many natural and managed ecosystems, are of particular concern5,6,7,8. Threats to honey bee health include pathogens, agrochemicals, pollutants, dwindling food sources...
mitochondrial homeostasis Introduction Ovarian function is essential for female fertility and overall health,Citation1 with disruptions leading to negative consequences on individual well-being, personal autonomy, and familial contentment.Citation2 Various factors, including genetics, environmental conditions, and...
[30]. Moreover, aerobic exercise significantly improves mitochondrial content and quality, enhancing mitochondrial biogenesis and potentially delaying mitochondrial function deficiencies. It also regulates tumor vasculature and oxygenation, leading to the development of more mature, and less permeable vessels ...
(GSH) and its precursor amino acids glycine and cysteine may be contributory. Supplementation with GlyNAC (combination of glycine andN-acetylcysteine as a cysteine precursor) was found to improve/correct cellular glycine, cysteine, and GSH deficiencies; lower OxS; and improve mitochondrial function, ...
Mitochondria play a pivotal role in the generation of signals coupling metabolism with neurotransmitter release, but a role for mitochondrial-produced ROS in regulating neurosecretion has not been described. Here we show that endogenously produced hydrog
hypercholesterolaemia and hyperleptinaemia and ameliorate impaired glucose and insulin tolerance. The effect of monthly FMD cycles on gene expression associated with mitochondrial metabolism and biogenesis in adipocytes and the sustained ketogenesis in HFCD-fed mice indicate a role for fat cell reprogrammi...
T. Carbonic anhydrase activators: an activation study of the human mitochondrial isoforms VA and VB with amino acids and amines. Bioorg. Med. Chem. Lett. 17, 1336–1340 (2007). Article CAS PubMed Google Scholar Jiang, C. et al. Intestine-selective farnesoid X receptor inhibition improves ...