In the sensitivity analyses, we performed a lagged analysis of the exposure for 2 or 4 years, which could strengthen the temporality and allow a time window for the development of microvascular complications. The creatinine levels (continuous, µmol/L) and frequency of meat intake (times/week...
Serum lipid levels Lipid-lowering medications were decreased in 4 participants (1 in the high wheat fiber diet arm, 3 in the low-GI legume diet arm) and increased in 1 participant in the high wheat fiber diet arm, with no significant treatment difference (P = .21). The low-GI legume...
biomarkers (Table 1) met the criteria for Baron and Kenny for mediation,26 except for systolic blood pressure, LDL cholesterol, TGs, LDL particle concentration, TG-rich lipoprotein particle concentration, TG-rich lipoprotein particle size, Lp(a), Apo B100, alanine, citrate, and creatinine. Howeve...
In the sensitivity analyses, we performed a lagged analysis of the exposure for 2 or 4 years, which could strengthen the temporality and allow a time window for the development of microvascular complications. The creatinine levels (continuous, µmol/L) and frequency of meat intake (times/week...
High-protein diets have additional benefits for NAFLD outcomes. However, excessive protein intake can also increase serum creatine levels, as observed in one participant during the study period, indicating that renal function should be monitored in susceptible individuals. We also found that intensive...
Even a moderate impairment in the glomerular filtration rate and creatinine clearance may result in hyperhomocysteinemia, especially for the elderly people. The genetic factors also influence the concentration of plasma Hcy. The methylenetetrahydrofolate reductase (MTHFR) C677T variant, the most common...
Time-restricted eating (TRE), a popular form of intermittent fasting, has shown benefits for improving metabolic diseases and cardiometabolic health. However, the effect of TRE in the regulation of blood pressure in primary hypertension remains unclear.
Thus, gut microbiota is considered as a target for future preventation of hyperuricemia. In the review, the feature and pathogenesis of hyperuricemia, the induction of diet on hyperuricemia, the association between hyperuricemia and gut microbiota, and the regulation strategies of gut microbiota on ...
(mmol mol − 1) Creatinine (μmol l − 1) CVD RA (% 5-year risk) 96.9 (7.4) 34.2 (2.3) 5.5 (0.6) 1.4 (0.3) 3.5 (0.5) 1.4 (0.2) 4.2 (0.5) 110 (5) 132 (7) 78 (3) 37 (2) 75 (4) 12.2 (1.9) 95.3 (7.7) 33.5 (2.4) 5.3 (0.8) 1.3 (0.5) 3.1 (0.7) 1.5 (...
Creatinine clearance was measured as a safety variable for the monitoring of renal function. Definitions, calculations, and statistical analysis The primary outcome variables were fasting plasma tHcy concentration at the end of each treatment period, which was based on the average of concentrations on ...