With the advent of very potent lipid-lowering therapies, the use of dietary approaches to controlling lipid levels has become de-emphasized in much of the developed world. While drug treatments (especially for elevated LDL cholesterol levels) are very effective, the role of diet in promoting hyper...
Figure 2. The Proportion of All-Cause Mortality Reduction for High Adherence to the Mediterranean Diet Attributed to Groups of Mediators View LargeDownload Mediator groups were small-molecule metabolites (citrate, creatinine, homocysteine, alaline), inflammation (high-sensitivity C-reactive ...
The kidney function also plays an important role in the regulation of Hcy levels. Even a moderate impairment in the glomerular filtration rate and creatinine clearance may result in hyperhomocysteinemia, especially for the elderly people. The genetic factors also influence the concentration of plasma ...
High-protein diets have additional benefits for NAFLD outcomes. However, excessive protein intake can also increase serum creatine levels, as observed in one participant during the study period, indicating that renal function should be monitored in susceptible individuals. We also found that intensive...
Intestinal tract is an important organ for lowering serum uric acid in rats[J]. PLoS One,2017,12(12):e0190194. doi: 10.1371/journal.pone.0190194 [47] XU D, LV Q, WANG X, et al. Hyperuricemia is associated with impaired intestinal permeability in mice[J]. AJP Gastrointestinal and ...
Serum liver enzymes, creatinine, calcium, phosphorus, alkaline phosphatase, thyreotropin and thyroid hormones were evaluated in all children and re-evaluated in the hypercholesterolemic group within 6–12 months after the dietary intervention. Statistical analysis was performed using STATA for Windows v...
Blood was extracted under standard conditions between 08.00 and 10.00 h following a 10– 14 h fast; extractions began after the subjects had been seated for a minimum 5 min and had shown venous sta- sis for under 2 min. Glucose, creatinine, urea, albumin, aspartate amino- transferase, ...
In the sensitivity analyses, we performed a lagged analysis of the exposure for 2 or 4 years, which could strengthen the temporality and allow a time window for the development of microvascular complications. The creatinine levels (continuous, µmol/L) and frequency of meat intake (times/week...
Creatinine, triglycerides, and cholesterol were measured by an enzymatic colorimetric assay and HDL by a homogeneous enzymatic colorimetric assay from Roche Diagnostics. For detailed assay information, please see supplemental Table 1. Histology Slices were stained with H&E for standard morphological ...
It has recently been proposed that the inherent lower dietary acid load of a DASH-type dietary pattern may partly explain the BP-lowering effects of this diet.21 In addition, in children, adherence to this nutritional regimen seems to be beneficial for long-term BP development.22 Of the two...