Dietary fat is an important part of the diet for humans to obtain lipids and energy. However, it is well known that excessive fat intake could lead to an accumulation of adipose tissue in the body and finally results in obesity and the development of a cluster of metabolic diseases, such ...
Dogs with IBD tend to lose protein in their feces, potentially leading to protein malnutrition, and therefore their diet should be made up of at least 25% DM protein and be highly digestible. Not only does the amount of protein matter, but so does the source. It is suspected that dietary...
For example:People with Hashimoto’s thyroiditis who followed the AIP diet for 12 weeks saw improvements in their quality of life, mental state, stress levels, and chronic conditions related to Hashimoto’s 8. People with active inflammatory bowel disease (IBD) had better quality of life when ...
Short chain fatty acids and its producing organisms: an overlooked therapy for IBD? EBioMedicine 66, 103293 (2021). Article CAS PubMed PubMed Central Google Scholar Park, S. Y. et al. Strain-level fitness in the gut microbiome is an emergent property of glycans and a single metabolite. C...
Recently, quantitative and qualitative changes in the composition of the gut microbiota have been detected in Crohn's disease and ulcerative colitis, reinforcing the hypothesis of dysbiosis as a relevant mechanism underlying inflammatory bowel disease(IBD) pathogenesis. Humans and microbes have coexisted ...
Their potentially common microbial drivers advocate for treatment strategies aimed at restoring appropriate microbiome function, but individual variation in host factors makes a uniform approach unlikely. In this Perspective, we consolidate knowledge on diet–microbiome interactions in local inflammation, gut ...
While hamsters typically have a high percentage of HDL-C when fed a low fat/low cholesterol diet (similar to rats and mice), dietary cholesterol alone will increase LDL-C and, like in humans, saturated fat can increase these levels further (Otto et al., 1995; Alexaki et al., 2004). ...
For instance, IBD patients tend to have less bacterial diversity as well as lower numbers of Bacteroides and Firmicutes—which together may contribute to reduced concentrations of microbial-derived butyrate. Butyrate and other SCFAs are thought to have a direct anti-inflammatory effect in the gut [...
For instance, IBD patients tend to have less bacterial diversity as well as lower numbers of Bacteroides and Firmicutes—which together may contribute to reduced concentrations of microbial-derived butyrate. Butyrate and other SCFAs are thought to have a direct anti-inflammatory effect in the gut [...
Accordingly, higher activity of NOS2, which contributes to the microbicidal activity of macrophages in the host, were found to contribute to onset of IBD in children below 10 years of age81. Further, increased abundance of Saccharomycetales was previously demonstrated in the ileum of patients ...