Diclofenac Sodium is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 nM, 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1, 0.84 μM for ovine COX-1 and COX-2, respectively. Diclofenac sodium is the sodium salt of diclofenac. It...
Diclofenac 75 to 150mg daily administered orally, rectally or intramuscularly is an effective analgesic and anti-inflammatory agent in the treatment of various rheumatic conditions (e.g. tendinitis, bursitis, sciatica, myalgia) and acute soft tissue injuries (e.g. strains, sprains). It is also ...
Diclofenac Sodium (GP 45840) is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells[1], and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively[2]. Diclofenac Sodium induces apoptosis...
ChEBI: Diclofenac sodium is the sodium salt of diclofenac. It contains a diclofenac(1-). Manufacturing Process Four grams of N-chloroacetyl-N-phenyl-2,6-dichloroaniline and 4 grams of aluminum chloride are well mixed together and heated for 2 hours at 160°C. The melt is cooled and poured...
Use of Diclofenac sodium Diclofenac Sodium is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 nM, 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1, 0.84 μM for ovine COX-1 and COX-2, respectively. ...
Remain alert for signs and symptoms of GI ulceration and bleeding during NSAID therapy. If a serious GI adverse event is suspected, promptly initiate evaluation and treatment, and discontinue diclofenac sodium delayed-release tablets until a serious GI adverse event is ruled out. ...
Diclofenac Sodium is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 nM, 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1, 0.84 μM for ovine COX-1 and COX-2, respectively. Diclofenac sodium is the sodium salt of diclofenac. It...
Diclofenac sodium topical gel is used for the relief of the pain of osteoarthritis of joints, such as the knees and those of the hands. Akorn receives FDA approval for topical gel They were given aspirin (150mg) once a day and diclofenac sodium 50mg three times a day for six consecutive ...
Diclofenac sodium enteric-coated and delayed-release tablets: 25 mg orally 4 times a day. An additional 25 mg dose may be administered at bedtime, if necessary Maximum dose: 125 mg per day Use: For acute or long-term use in the relief of signs and symptoms of ankylosing spondylitis. ...
Diclofenac sodium is a potent nonsteroidal anti-inflammatory drug with analgesic activity. When instilled as a topical 0.1% solution in a limited number of patients undergoing cataract surgery, diclofenac limits surgically induced miosis, reduces signs of ocular inflammation, does not cause elevations in...