Diclofenac (administered orally, rectally or intramuscularly as single doses of 50 to 100mg or up to 150mg daily) is an effective analgesic agent in cases such as dental or minor surgical pain, postpartum pain and headache. It was at least as effective as usual therapeutic dosages of NSAID...
Huskisson EC, Bryans R. Diclofenac sodium in the treatment of painful stiff shoulder. Curr Med Res Opin 1983; 8(5):350- 353.↵ Huskisson EC , Bryans R . Diclofenac sodium in the treatment of painful stiff shoulder. Curr Med Res Opin 1983 ; 8 : 350 – 3 ....
Stability Stable. Water Solubility H2O: 50 mg/mL MSDS Diclofenac sodium MSDS(Chinese) Toxicological Information CHEMICAL IDENTIFICATION RTECS NUMBER : AG6330000 CHEMICAL NAME : Acetic acid, o-(2,6-dichloroanilino)phenyl-, monosodium salt CAS REGISTRY NUMBER : 15307-79-6 LAST UPDATED : ...
Diclofenac sodium Properties Melting point288-290°C Density0.781 g/cm3 storage temp.room temp solubilityH2O: 50 mg/mL pka4(at 25℃) formWhite solid colorWhite to Almost white biological sourcesynthetic Water SolubilitySoluble in water to 50mg/ml. ...
Diclofenac sodium is available in an EC formulation (Voltaren) and as a potassium salt (Cataflam). Voltaren is available in the US as 25-, 50-, and 75-mg EC tables, with the adult dose ranging between 75 and 225 mg/day. A combination tablet containing diclofenac, 50 mg (Arthrotec 50)...
One of the two topical vs. oral diclofenac studies was a 12-week double-blind, double-dummy study comparing topical diclofenac solution (1.5% diclofenac sodium in 45.5% dimethyl sulfoxide [DMSO]) with oral diclofenac capsules 50 mg three times daily (the maximum daily dose) in patients with ...
Diclofenac is a phenylacetic acid. In addition to inhibiting COX, diclofenac diminishes the availability of arachidonic acid by stimulating its uptake and inhibiting its release. Diclofenac sodium is available in an EC formulation (Voltaren) and as a potassium salt (Cataflam). Voltaren is available ...
Doses of the potassium salt are similar to those for diclofenac sodium. Diclofenac potassium is also used in the treatment of migraine in an initial dose of 50 mg taken at the first signs of an attack; an additional dose of 50 mg may be taken after 2 hours if symptoms persist. If ...
sodium diclofenac tablets were notable. TheCmaxachieved after administration of a diclofenac potassium immediate-release 50-mg tablet was slightly lower (Table2), but thetmaxwas substantially shorter (range 0.63–1.26 h) than that of a diclofenac sodium enteric-coated 50-mg tablet (range 1.13–...
(Trojanowicz et al.2012). The sterilization dose for DCF sodium salt, as a pharmaceutical raw material, has been found to be 12.4 kGy (60Co) (Ozer et al.2013). Homlok et al.2011described complete removal of DCF with 1.0 kGy. When cost is an issue, it is difficult to give a ...