diflunisal, salsalate) is not recommended due to the increased risk of gastrointestinal toxicity, and little or no increase in efficacy(seeWARNINGS; Gastrointestinal Bleeding, Ulceration, and PerforationandDrug Interactions).Alert patients that NSAIDs may be present in “over the counter”...
Eligible patients were given 28 FDETS, each containing 180 mg of diclofenac epolamine, equivalent to 140 mg of diclofenac sodium. Data from a pharmacokinetic study in healthy adult volunteers show that approximately 5–6% of the diclofenac epolamine content of a patch is released during the 12-...
Different formulations of diclofenac (diclofenac sodium delayed-release tablets; diclofenac sodium extended-release tablets; diclofenac potassium immediate-release tablets) are not necessarily bioequivalent even if the milligram strength is the same. HOW SUPPLIED SECTION Diclofenac sodium delayed-release tablets...