A microcapillary method for the diagnosis of sickle-cell disease in which a sample of unclotted blood is mixed with a reagent comprising phosphate buffer containing a non-ionic surfactant having high water solubility, a hemolyzing agent and a reducing agent, and the reaction results observed ...
Over the years, with technological advances, additional treatable or manageable metabolic disorders have been added to NBS programs.13–18 Second-tier DNA molecular analysis after NBS has been used for confirmation of common mutations for sickle cell disease (OMIM 141900),19 cystic fibrosis (OMIM ...
Sickle cell disease persons are prone to develop nephropathy due to the hemoglobinopathy, infection or drug therapy. Any indication of nephropathy or urinary tract abnormality can be ascertained, using urine analysis. In this study, spot urine samples were collected from 294 SCD subjects, aged 5 to...
Results of minimally toxic nonmyeloablative transplantation in patients with sickle cell anemia and β-thalassemia - ScienceDirect We describe previously transfused patients with sickle cell disease (n = 6) and thalassemia (n = 1) who received nonmyeloablative hematopoietic stem cell t... R Iann...
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Gene therapy for sickle cell disease. Cochrane Database Syst Rev. 2018. https://doi.org/10.1002/14651858.CD007652.pub6. Article PubMed PubMed Central Google Scholar Sampara P, Banala RR, Vemuri SK, et al. Understanding the molecular biology of intervertebral disc degeneration and potential...
Assessment of cystatin C in pediatric sickle cell disease and β-thalassemia as a marker of subclinical cardiovascular dysfunction: a case-control study. Pediatr Hematol Oncol. 2021;38(7):620–632. 37. Angelidis C, Deftereos S, Giannopoulos G, et al. Cystatin C: an emerging biomarker in ...
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Editorial: First Regulatory Approvals for CRISPR-Cas9 Therapeutic Gene Editing for Sickle Cell Disease and ... DOI :10.12659/MSM.944204 Med Sci Monit 2024; 30:e944204 0:00 28 Jan 2024 :Review article17,066 A Review of IgA Vasculitis (Henoch-Schönlein Purpura) Past, Present, and Future...
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