We identified all activities such as blood and plasma collection, DNA extraction, genomic analysis, interpretation of results and sign-out of diagnostic report (Fig. 2). In each of the steps, the use of resources was captured, such as consumables (including laboratory reagents), equipment use ...
As discussed in this report, The Worldwide Market for Point-of-Care (POC) Diagnostic Tests, 9th Edition, POC testing has skyrocketed in the last 20 years as demand for accurate and rapid testing has blossomed both inside and outside the hospital setting. An in-depth look at the global POC...
for example, shows the ‘FINDINGS’ section of the report. Although we are not aware of any clearly articulated description of the exact goals of research on DC systems, the main goals seem to be to (a) increase
Phosphofructokinase, platelet (PFKP) is a rate-limiting enzyme of glycolysis that plays a decisive role in various human physio-pathological processes. PFKP has been reported to have multiple functions in different cancer types, including lung cancer and
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The SWEETRkit 1.0 (Supplementary Table1) contains aSWEETpromoter database (SWEETpDB), SWEETupprimers for detecting mRNA accumulation for eachSWEETgene, three SWEETacc-rice tester lines that report spatial SWEET protein accumulation during infection using translational reporter fusions26, single- and co...
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In this report, we describe the generation of antibodies targeting core tau. The antibodies were characterised using peptide mapping, epitope binning and scanning mutagenesis, followed by affinity ranking by ELISA and surface plasmon resonance. This panel of antibodies was used to develop sensitive sand...
Noncommunicable diseases are the predominant cause of death worldwide. According to a 2012 WHO World Health Statistics report, mortality rates from noncommunicable diseases are rising and account for approximately 60 % of deaths per year in low- and middle-income countries [19]. Therefore, these di...
Mutations in H3F3A and H3F3B encoding histone 3.3 cause the first reported germline histone syndrome: report of 23 patients with neurodevelopmental and congenital manifestations. In: 38th Annual David W. Smith Workshop on Malformations and Morphogenesis: Abstracts of the 2017 Annual Meeting. Am...