Among others, PD-L1, ERG, Integrin-β5, Survivin, TGF-β, phosphorylated-TSC2 as well as partners of the MAP-kinase and mTOR pathways emerged as differentially expressed endpoints in tumor-derived EVs. In addition, the retrospective analysis of EVs from a 15-year follow-up cohort generated ...
Schematic diagram showing extracellular vesicle (EV) generation and pathogenic prion protein (PrPTSE) localisation in EVs. Small EVs (exosomes; < 200 nm) are generated via endosomal pathways when the multivesicular bodies (MVBs) fuse with the plasma membrane. These carry several classes of mark...
Research into the preclinical diagnosis of AD has provided considerable evidence regarding early neuropathological changes using brain Aβ imaging and the cerebrospinal fluid biomarkers, Aβ and tau. Both these approaches have limitations that are expensive, invasive or time consuming and thus preclude...
However, a high proportion of children with Respiratory Syncytial Virus positive bronchiolitis were found to have radiographs consistent with the WHO radiological definition for pneumonia (consolidation of a lobe or whole lung); indicating that imaging has reduced predictive value for bacterial disease in...
UniversitàdiSiena,PoliclinicoLeScotte,Siena,Italy j CentreforNeuromuscularandNeurologicalDisorders,M518,UniversityofWesternAustralia,Nedlands,Australia k InstituteofNeurology,CatholicUniversity,Pol.Gemelli;IRCCSS.Raffaele-PisanaandCasadiCuraS.Raffaele-Cassino,Roma,Italy l DepartmentofNeurology,Goethe-University...
The description for Diagnostic Radiology notes: “Get your hands on a revolutionary new way to master abdominal imaging and access the knowledge of today’s experts on tomorrow’s technology”. Similarly, Visual DX provides images that would otherwise be difficult to access in the diagnostic ...
UniversitàdiSiena,PoliclinicoLeScotte,Siena,Italy j CentreforNeuromuscularandNeurologicalDisorders,M518,UniversityofWesternAustralia,Nedlands,Australia k InstituteofNeurology,CatholicUniversity,Pol.Gemelli;IRCCSS.Raffaele-PisanaandCasadiCuraS.Raffaele-Cassino,Roma,Italy l DepartmentofNeurology,Goethe-University...
Department of Traumatology, John Hunter Hospital, Newcastle, NSW 2308, Australia * Author to whom correspondence should be addressed. † These authors contributed equally to this work. Biomolecules2023,13(11), 1625;https://doi.org/10.3390/biom13111625 ...
Heart failure (HF) is the leading cause of hospitalisations worldwide, with only 35% of patients surviving the first 5 years after diagnosis. The pathogenesis of HF with preserved ejection fraction (HFpEF) is still unclear, impeding the implementation of