A number of factors influence the metabolism of vitamin D. These include season, geographic location, race, body habitus, pregnancy, lactation, age, and drugs. Individuals with pigmented skin make less vitamin D and, as a consequence, may have low serum vlaues for vitamin D and 25-...
Seasonal variation is an important aspect of vitamin D biology in northern latitudes, such as in the UK. In the light of the findings of Haroon et al., we aimed to explore this variable in more depth over a full year, whilst seeking any relationship between vitamin D levels and ...
In clinical practice, the finding of an elevated mean corpuscular volume (MCV), or specific neurological symptoms is often the reason to test for vitamin () deficiency. Use of the MCV as a test for the detection or exclusion of deficiency is only justified if the diagnostic accuracy is suffic...
There are two types of vitamin D dependent rickets (VDDR) that cause rickets in children. Vitamin D dependent rickets type 1 (VDDR-I) is caused by an inborn error of vitamin D metabolism, which interferes with renal conversion of calcidiol (25OHD) to calcitriol (1,25(OH)2D) by the ...
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Biomarkers of Inflammation, Vitamin D, and Colorectal Cancer Risk and SurvivalAbstract Environmental and genetic factors are believed to contribute to Neurodegenerative disorders such as Amyotrophic Lateral Sclerosis, Parkinson's, Huntington and Alzheimer's diseases. In general, these diseases are poorly ...
The authors proceeded to review the various sources and origins of neuronal oxidative stress and reviewed the known intrinsic metabolic mechanisms for natural protection against such stress. They mentioned the ability of vitamin E to inhibit lipid peroxidation (pg. 690, first column, lines 5-9), ...
Wong-See DKatz TGaskin KWhitehead BJaffe ACoakley JLochhead A###Dysken MWGuarino PDVertrees JEMayéuticaSantiago M, Martinelli R, Reis MG et al (2004) Diagnostic performance of anti-beta2 glycoprotein I and anticardiolipin assays for clinical manifestations of the antiphospholipid syndrome. Cli...
(TPA) or to erythrocytes with hemin, and HL60 cells differentiated to macrophages using TPA or to monocytes using vitamin D3 (FIG. 4). Only a few miRNAs were consistently upregulated (by at least 40%) in all four systems of terminal differentiation: miR-22, miR-125a and members of ...
ies Have a Role?]]>doi:10.1016/j.jaci.2012.12.781James A. LohAmin S. KananiDonald F. Starkretour au numéro