internal medicineABSTRACT Background Trephine bone marrow biopsy (BMB) in internal medicine has only been studied in fever of unknown origin and inflammation of unknown origin. The aim was to asses... 查看全部>>Jean-Philippe MartellosioMathieu Puyade...
Extracellular vesicles (EVs) and their cargo represent an intriguing source of cancer biomarkers for developing robust and sensitive molecular tests by liquid biopsy. Prostate cancer (PCa) is still one of the most frequent and deadly tumor in men and analysis of EVs from biological fluids of PCa...
Besides tumor biopsy specimens, microRNA can be assessed in serum, plasma and bone marrow smears.120,121 A five-miRNA serum signature has been shown to be predictive of prognosis for diffuse large B-cell lymphoma patients treated with R- CHOP.122 Tissue miRNAs seem to be more reliable in ...
27 Bone marrow possible − − − transplant 28 Oncology possible − − 5.05 29 AML possible − − 0.47 30 Heart probable 1.22 − 3.52 transplant 31 AML possible − − − 32 Haematological possible − − 14.26 oncology 33 MS possible − − − 34 B-cell ...
Stem cells are isolated for transduction and differentiation using known methods. For example, stem cells are isolated from bone marrow cells by panning the bone marrow cells with antibodies which bind unwanted cells, such as CD4+ and CD8+ (T cells), CD45+ (panB cells), GR-1 (granulocytes...
In order to replace muscle biopsy in patients affected by DMD non-invasive biomarkers with diagnostic value and prognostic applications have been investigated for a long time. Recently it was shown that the serum levels of some muscle-specific miRNAs were modified in DMD, specifically miR-1, 20,...
fungal transcriptome resembling response to phagocytosis, suggesting that phagocytes contribute significantly to fungal control in the liver [176]. Rasmussen et al. combined longitudinal , dimensionality reduction and categorical analysis of the transcriptome from 111 liver biopsy specimens taken from 57 ...
(in the form of valganciclovir), or intravitreally. However, the usage of ganciclovir is limited due to the need for a compounding pharmacy to prepare the medication [37]. Furthermore, systemic use of ganciclovir and valganciclovir may lead to severe side effects such as bone marrow suppression...
Extracting diagnostic data from unstructured bone marrow biopsy reports of myeloid neoplasms utilizing a customized natural language processing (nlp) algorithm. Blood 132, 2272–2272 (2018). Article Google Scholar Yala, A. et al. Using machine learning to parse breast pathology reports. Breast ...
Herein, “biological sample” means a sample of cells from a patient. These cells may be part of a tissue or organ sample obtained, for example, by biopsy, or they may be individual cells, for example, bone marrow cells, blood cells or even cells grown in culture. Preferably, such cells...