Cardiac amyloidosis is a life-threatening disease that occurs when amyloid proteins, most com- monly immunoglobulin light chain or trans- thyretin, mutate or become unstable, misfold, deposit as amyloid fibrils, and accumulate in the myocardium. Early diagnosis of cardiac amyloidosis is hindered by...
Cardiac amyloidosis is a rare condition with only 2,500 new cases reported yearly in the United States of America (USA). The prognosis of cardiac amyloidosis is particularly grim. The median survival is 6 months from onset of congestive heart failure (CHF) symptoms. CHF is a common ...
Introduction The diagnosis of cardiac amyloidosis (CA) is usually performed by endomyocardial biopsy; however, possible sampling errors and procedural risks such as cardiac tamponade, malignant arrhythmias and bleeding risk, limit its use. Therefore, a non-invasive diagnostic method appears to be ...
Major Subject Heading(s)Minor Subject Heading(s) Amyloidosis [diagnostic imaging] Humans Myocardium Tomography, X-Ray Computed PreMedline Identifier: 36255317From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.Printer...
The cause of severe right heart failure and of equal diastolic pressures in both ventricles (as seen in constrictive pericarditis) in a 56-year-old woman was suspected to be cardiac amyloidosis on the basis of findings in both the echocardiogram (biventricular hypertrophy) and the electrocardiogram...
Noninvasive Diagnosis of Cardiac Amyloidosis by MRI and Echochar diography Jing WANG(汪晶)1,Xiangquan KONG(孔祥泉)1#,Haibo XU(徐海波)1,Guofeng ZHOU(周国锋)1,Dandan CHANG(常丹丹)1,Dingxi LIU(刘定西)1,Li ZHANG(张丽)2,Mingxing XIE(谢明星)2 1Department of Radiology,2Department of Ultrasound,...
of CVDs were incorporated with the following distribution: hypertrophic cardiomyopathy (HCM; 2,715), dilated cardiomyopathy (DCM; 1,639), coronary artery disease (CAD; 1,241), left ventricular noncompaction cardiomyopathy (LVNC; 321), restrictive cardiomyopathy (RCM; 377), cardiac amyloidosis (CAM...
The heart is commonly involved in various forms of amyloidosis and cardiomyopathy is a major cause of morbidity and mortality in these patients. Diagnosis of cardiac amyloidosis is often delayed due to nonspecific presenting symptoms and failure to recognize early signs of amyloid heart disease on rou...
"The heart is the most important abnormality in amyloidosis because if the heart is affected, that is the complete driver of how the patient will do and what their prognosis is," says Dr. Grogan. "That's why cardiac amyloidosis is so important to recognize and treat as early as possible....
Objective To assess the value of echocardiography combined with electrocardiogrpahy (ECG) in diagnosis of cardiac amyloidosis. Methods The echocardiography and ECG examination in the 20 patients with cardiac amylodosis,which were diagnosed by pathological examination,were retrospectively analyzed,especially ...