Correlation between freePSA/total PSA ratio and the prostate cancer diagnosis using transrectal ultrasound guided prostate biopsydoi:10.1016/S1569-9056(18)33490-0Constantin T.V.Brinzan D.M.Popescu R.Dida T.Ambert V.Radu T.Calin C.Andrei S.C....
We investigated an optimal cutoff level of free/total PSA ratios (f/t PSA) in predicting prostate cancer in different age groups, focusing on the avoidance of unnecessary prostate biopsies. A total of 4955 men were enrolled into the study. Serum tPSA, fPSA, and f/t PSA ratioswere determine...
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Total and free serum PSA determinations were performed using three types of electro-chemiluminescence immunoassays recalibrated to the World Health Organization (WHO) standard. The diagnostic accuracy of PSA, %fPSA, and %fPSA in combination with PSA (%fPSA + PSA) was determined using the area ...
This study investigated the efficacy of the elastography strain ratio (ESR) as a predictor of prostate cancer (PCa) in targeted prostate biopsy. In total, 257 patients who underwent magnetic resonance imaging-targeted biopsy were enrolled. Before biopsy,
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A reliable and non-invasive diagnostic/prognostic procedure is thus still lacking, even tough novel methodologies based on the simultaneous measurement of various parameters (e.g. free and total PSA) are emerging as tools to increase the overall diagnostic accuracy. Most PSA in the blood is bound...
Provided herein are assays and methods related to determining a ratio of expression levels of PSA/PSMA or determining the expression level of PSMA in circulating tumor cells for diagnosis and/or for the purpose of monitoring treatment efficacy for prostate cancers that are likely hormone resistant.In...
However, the disadvantages of this method are the still unsatisfactory rates for sensitivity and specificity (Kirby et al. 2009; BJU Int.; 103(4):441-5.). A further commonly used test to asses the presence of prostate cancer is the Prostate Specific Antigen (PSA) (kallikrein-related ...
In this study, we report on an antibody based porous silicon fluorometric microarray immunoassay platform for simulateous detection of serum levels of both total PSA and hK2. The surface of porous silicon has a 3-dimensional macro- and nanoporous structure, which offers a large binding capacity ...