FIG. 18 The distant metastases probability as a function of time since diagnosis for progesterone receptor (PR)(+) (yes) or PR(−) (no) individuals. FIGS. 19A, B The distant metastases probability as a function of time since diagnosis. Groups were defined by the tumor grades. FIG. 20A...
Sara M. Tolaney, MD, MPH, states that all breast cancers should be tested for estrogen, progesterone, and HER2 receptors; HER2 testing involves an immunohistochemistry stain to quantify protein levels, with 3+ indicating HER2+ disease, 0 indicating HER2- disease, and 1-2+ levels...
Stage may be considered a predictor and outcome of delay, because clinical prognosis and chemotherapy treatment choices for breast cancer are determined by stage, and nodal status, tumor size, and estrogen and progesterone receptor status30; these factors were included in all analyses. We adjusted ...
If you want to truly understand cholesterol, I highly recommend engineer Dave Feldman's pioneering work, which he shares on his websiteCholesterol Code.Dave's mission is to get to the bottom of the cholesterol story by explaining how cholesterol works in the body, why some people on low-carb...
progesterone receptor component 1 44592 1523.67 21.9661 44633 1523.84 29.7538 VIDQSRVLNLGPIT Uromodulin UROM_HUMAN (592-605) 44679 1524.65 20.0263 44802 1526.69 23.9186 45021 1532.62 26.3459 45243 1535.68 22.0021 VEHSDLSFSKDWS Beta-2-microglobulin B2MG_HUMAN ...
[9] demonstrated that mucin 1, a cell surface associated antigen (MUC1) is a much more important biomarker (BM) than the other known biomarkers such as estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2) in BC. In a study carried out ...
So far, only three validated predictive factors of benefit from standard (neo)-adjuvant treatments exist in EBC: (1) estrogen receptor (ER), (2) progesterone receptor (PgR), and (3) HER2 (over)-expression. These factors are routinely used for the selection of patients for HT (with the ...
After treatment with DNase I containing suspension medium (L15 with 3.6 mg/ml glucose, 20 nM progesterone, 5 ug/ml insulin, 0.1 mM putrescin, 0.1 mglml conalbumin, 30 nM sodium selenite, 100 IU/ml penicillin, 100 ug/ml streptomycin, 2 % horse serum, 1x Glutamax I and 0.1 mg DNase...
tricyclic or tetracycline antidepressant, typical or atypical antipsychotic (including but not limited to olanzapine, risperidone, quetiapine, ziprasodone, aripiprazole), triiodothyronine, T4, estrogen and progesterone compounds and derivatives (SERMs, etc), anxiolytic sedative, whether of benzodiazepine or ...
They tend to be larger and higher grade than screen-detected cancers, more likely estrogen receptor negative (ER-)and progesterone receptor negative (PR-negative), more likely mucinous and lobular histology, more likely with nodal metastases at the time of diagnosis, and with a higher ...