concerns have been focused on opioid use in the context of chronic noncancer pain (CNCP), risks for people with cancer may also be growing as medical advances translate to people are living longer with the ‘chronic’ phase of advanced disease and continuing on opioid therapy for extended ...
heart rhythm abnormalities, heart failure, and increased mortality. JAMA Associate Editor Anne Cappola, MD, speaks with Elizabeth N. Pearce, MD, MSc, of Boston University, about the most common causes, symptoms, and first-line treatments for hyperthyroidism....
(PICCK) Providers Clinical Support System - Medications for Opioid Use Disorders (PCSS-MOUD) Radiology Health Equity Coalition (RHEC) SAGECare Society of Critical Care Medicine (SCCM) Society of Hospital Medicine Stanford Medicine University of California Center for Climate, Health and Equity Veterans...
Prescribing of opioid and concomitant sedative prescriptions (including benzodiazepines, Z-drugs, and barbiturates) were identified by the Multum lexicon code. Multivariable logistic regression evaluated the risk of opioid prescribing or co-prescribing of opioid and sedative associated with ADRD in older ...
This diagnostic requirement would exclude, for instance, surgical patients given opioid drugs for the relief of pain, who may show signs of an opioid withdrawal state when drugs are not given but who have no desire to continue taking drugs. The dependence syndrome may be present for a specific...
related research has identified of insulin-like and opioid growth factors or proteins such as ADAM9, cathepsin B and neuropilin-1 as key components of the secretome of head and neck tumor or glioblastoma cells47,48. Circulating PBMCs respond to such tumor secretome signals with functional and ph...
Lung cancer remains a major health concern worldwide1,2, underscoring the urgent need for effective strategies that can reduce lung cancer-related mortality. Early diagnoses are vital for improving clinical outcomes by facilitating timely interventions3; however, the acknowledged noninvasive lung cancer ...
Dislocated hips in newborns can lead to complex surgery, interruption to family life, and premature osteoarthritis. Daniel Perry, MBChb(Hons), PhD, of Alder Hey Children's Hospital, University of Liverpool, discusses the clinical diagnosis of dislocated hips in newborns with JAMA Associate Editor Da...
multivariate Cox regression analysis, we found that the adjusted hazard ratio (aHR; 95% confidence interval [CI]) of all-cause death for the sarcopenia group compared to the nonsarcopenia group was 1.49 (1.43–1.55;p< 0.001). Additionally, the aHRs (95% CIs) of all-cause death for those...