Family history of cancermultiple neoplasmsDDR genesimmune checkpoint inhibitorsimmunotherapyPD-1Background: We investigate the role of family history of cancer (FHC) and diagnosis of metachronous and/or synchronous multiple neoplasms (MN), during anti-PD-1/PD-L1 immunotherapy. Design: This was a ...
Although having a family history of breast cancer is a well established breast cancer risk factor, it is not known whether it influences mortality after breast cancer diagnosis. We studied 4,153 women with first primary incident invasive breast cancer diagnosed between 1991 and 2000, and enrolled ...
Family history (FamH) of type 2 diabetes might indicate shared genotypes, environments, and/or behaviors. We hypothesize that FamH interacts with unhealthy behaviors to increase the risk of early onset of diabetes and poor cardiometabolic control. In a c
Radiomic features based classifiers and neural networks have shown promising results in tumor classification. The classification performance can be further improved greatly by exploring and incorporating the discriminative features towards cancer into ma
Mesothelioma Hope is committed to walking alongside you every step of the way. Our Patient Advocates are here to: Connect you with a mesothelioma specialist for a diagnosis or a second opinion Empower you with information and questions to ask your cancer care team Help you navigate your ...
Prolonged irritation of the gallbladder could lead tocancer of the gallbladder. Symptoms of Biliary Colic Symptoms of biliary colic are sudden onset with pain starting in the area above the umbilicus called the epigastrium, and move to the right upper quadrant of the abdomen. Symptoms may start...
An undescended testicle can lead to problems with fertility, make cancer more likely, and raise the odds of injury. Learn what to look for, what it can cause, and how it’s treated.
Characteristics of pancreatic cancer patients and matched controls at the time of prediagnosis imaging are shown in Table1. Cases were more likely than controls to have a history of diabetes and smoke cigarettes. Pain (abdominal, back, flank, or chest) was the most frequent indication for the ...
In general, the results confirmed the usefulness of the family history method. Although it has some limitations, such as underreporting, it has respectable sensitivity for many major diagnoses when broad but well-specified criteria are used. Full Text ...
Since the studied condition is AD, a type of dementia, our calculation of CCI omitted dementia and only included a total of 16 physical conditions that represent common conditions like cancer, diabetes mellitus, and cardiovascular disease. The matched GOA individuals were also required to have a ...