Mildly elevated MMA occurs in patients with mutations affecting methylmalonyl-CoA epimerase (MCEE) [2], [3]; and in patients with mutations affecting the ACSF3 gene [4], [5], in which malonic acid levels may be elevated as well. For the past 40 years the Vitamin B12 Clinical Research ...
yet standard medical practice is unable to diagnose most infections. Many infections are treatable, but it’s not easy to treat something you can’t diagnose. Getting a clear and accurate diagnosis of infections and treating them appropriately, along ...
Objectives The analysis of organic acids in urine is an important part of the diagnosis of inherited metabolic disorders (IMDs), for which gas chromatography coupled with mass spectrometry is still predominantly used. Methods Ultra-performance liquid chr
Maddox, et al., “Elevated Serum Levels in Human Pregnancy of a Molecule Immunochemically similar to Eosinophil Granule Major Basic Protein,” J. Exp. Med. 158:1211-1216 (1983). Mahvi, et al., “DNA Cancer Vaccines—A Gene Gun Approach,” Imm. and Cell Bio. 75: 456-460 (1997)....
The main limitations of the EUS are: (1) it is a relatively invasive procedure; (2) limited availability, needs to be performed in a center with high volume as the diagnostic accuracy is directly related to the operator's skills; (3) elevated costs, ranging from $2,152 to $2,605 per...
In addition to relatively high IGF-1 levels, elevated fasting GH levels in early infancy may contribute to the diagnosis of IGF1R abnormalities.Masato OnoMasato TanakaShota HiroshimaKentaro SawanoYohei OgawaKeisuke NagasakiAkihiko Saitoh