Combined, these findings indicated a likely underlying connective tissue disorder, and an indirect referral to a specialist in hypermobility syndromes confirmed a diagnosis of type III Ehlers鈥揇anlos syndrome with postural orthostatic tachycardia syndrome. This case highlights the importance of the dental...
S3, when audible, occurs early in ventricular filling and may represent tensing of the chordae tendineae and the atrioventricular ring, which is the connective tissue supporting the tricuspid and mitral valves valve leaflets. S4, when audible, is caused by vibration of the ventricular wall during...
Hirschsprung disease (HD) is a congenital disorder in the distal colon that is characterized by the absence of nerve ganglion cells in the diseased tissue. The primary treatment for HD is surgical intervention with resection of the aganglionic bowel. The accurate identification of the aganglionic...
The female breast is made up mainly of lobules (milk-producing glands), ducts (tiny tubes that carry the milk from the lobules to the nipple), and stroma (fatty tissue and connective tissue surrounding the ducts and lobules, blood vessels, and lymphatic vessels). Most breast cancers begin ...
In a study on 10 patients with the connective tissue disorder Ehlers-Danlos type IV syndrome (EDS IV), 9 patients were found to secrete a decreased amount of type III procollagen and one patient was found to secrete a structurally altered type III procollagen (Stolle et al., 1985). ...
(Leiden) mutation, previous diagnosis of APS, or other connective tissue disorder (CTD) were excluded. Control patients were recruited from patients admitted to the Orthopedic clinic for fractures or musculoligamentous disorders and without acute myocardial infarction, stroke, or other cardiac conditions...
In most clinical cases, peripheral blood eosinophilia is reactive and typically associated with non-hematological disorders such as infections, allergic conditions, connective tissue disorders, vasculitis, malignancy, or endocrinopathies. Nonetheless, the cause of most cases of hypereos...
PURPOSE:To enable effective diagnosis of a disorder in various connective tissues, by using a diagnosing drug comprising a monoclonal antibody against keratosulfate. CONSTITUTION:Keratosulfate is used as antigen to prepare a monoclonal antibody used for diagnosis by Caterson, et al's method or the ...
The methods of the present invention are useful for determining whether an individual has or is at risk of developing an affective disorder by detecting the expression level of connective tissue growth factor (CTGF) in a biological sample. The methods of the present invention are also useful for...
As used herein the term “effective amount” or “therapeutically effective amount” means a dosage sufficient to treat, inhibit, or alleviate one or more symptoms of the disorder being treated or to otherwise provide a desired pharmacologic and/or physiologic effect. The precise dosage will vary ...