Initially, to inhibit early fission, we treated cells with small interfering RNA (siRNA) against LPAAT−γ and then collected Golgi membrane as previously described16. When this Golgi membrane was used in the COPI reconstitution system, we found that PA with saturated acyl chains (2C18:0, se...
Application Number: 16/025199 Publication Date: 07/14/2020 Filing Date: 07/02/2018 Export Citation: Click for automatic bibliography generation Assignee: Metabasis Therapeutics, Inc. (San Diego, CA, US) International Classes: A61K31/675; A61K31/52; A61K31/542; A61K31/662; A61K31/665; ...
Yarrowia lipolytica ARE2 (“Yl ARE2”) 15 (1632 bp) 16 (543 AA) Mortierella alpina DGAT1 17 (1578 bp) 18 (525 AA) (“Ma DGAT1”) Mortierella alpina DGAT1 -internal 175 (604 bp) — cDNA fragment Neurospora crassa DGAT1 — 19 (533 AA) (“Nc DAGAT1”...