Diabetic retinopathy: An update.(Review Article)(Disease/Disorder overview)Singh, RamandeepRamasamy, KimAbraham, ChandranGupta, VishaliGupta, Amod
Of the five million known diabetics in the United States, 5,000 become blind each year because of diabetic retinopathy. While the pathologic changes in the retina are well defined, the pathogenetic and pathophysiologic factors are not clear, and therapeutic approaches are empirical. The disease may...
The grading of diabetic retinopathy is based on the concept that a hierarchy of stages can be defined, where the higher the grade, the higher the risk of suffering visual loss. The grading scale reflects the natural course of the disease in its unrelenti
Hyperglycaemia appears to be a critical factor in the aetiology of diabetic retinopathy and initiates downstream events including: basement membrane thickening, pericyte drop out and retinal capillary non-perfusion. More recently, focus has been directed to the molecular basis of the disease process in...
SummaryThis review has provided a chronologic background to our current understanding of diabetic retinopathy: epidemiologically, pathophysiologically, and in terms of treatment modalities. Our options for sight-saving and/or restoration have been greatly expanded over a short period of time, and continu...
Impairment of neuroprotection and vasculopathy are the main reasons for the progression of diabetic retinopathy. In this review, we decided to illustrate the molecular and clinical aspects of diabeti...
Advances in retinal imaging and applications in diabetic retinopathy screening: a review. Ophthalmol Ther. 2018;7:333–46. Article PubMed PubMed Central Google Scholar Tran KT, Mendel TA, Holbrook KL, Yates PA. Construction of an inexpensive, hand-held fundus camera through modification of a ...
The prevalence of diabetes in pregnancy is increasing. Pre-existing diabetes is present in 1 in 167 pregnancies in Australia, divided equally between type 1 and type 2 diabetes. Diabetic retinopathy is a leading cause of blindness in women during their c
Genentech provided ranibizumab for the study and funds to the Diabetic Retinopathy Clinical Research Network to defray the study’s clinical site costs. Role of the Funder/Sponsor: The National Institutes of Health participated in oversight of the conduct of the study and review of the manuscript ...
Diabetic retinopathy (DR) is a condition where the retina is damaged due to fluid leaking from the blood vessels into the retina. In extreme cases, the patient will become blind. Therefore, early detection of diabetic retinopathy is crucial to prevent blindness. The main stages of diabetic retin...