Based on the aforementioned data, more studies are needed to definitely evaluate the efficacy and safety of exenatide as an anti-obesity medication. Semaglutide, a long acting GLP-1 analogue, was administered o
In a clinical study with 60 Parkinson patients treated with exenatide (2 mg) once weekly for 48 weeks in addition to their usual medication, observed positive and enduring effects on off-medication motor scores as measured by MDS-UPDRS [63]. In a later analysis of the same study they achiev...
One week later, different nano-medicines were injected into the periodontium site (4 weeks, once/week) to investigate the therapeutic effects of ACFDG on periodontium in diabetic rats under NIR irradiation.The whole process of the in vivo experiment is shown in Figure5A. After the injection ...
Diabetic retinopathy has a high probability of causing visual impairment or blindness throughout the disease progression and is characterized by the growth of new blood vessels in the retina at an advanced, proliferative stage. Microglia are a resident immune population in the central nervous system, ...
Type 1 diabetes is characterized by total loss of beta cells so that the patient requires insulin by injection. Type 1 diabetes accounts for 10-15% of all diabetes. Type 1 diabetes is strongly associated with auto-antibodies and this association has become part of the definition/classification ...
In keeping with the AAN, we define 1) a lack of efficacy, when significant pain reduction is not achieved after titration to an effective dose and duration; 2) intolerability, when the adverse effects caused by a medication outweigh the symptomatic benefit; and 3)...
Now, to understand some of the investigators results, you need to know their definitions.Diabetes remission= glycemic control without medication use.Partial remissionis “sub-diabetic hyperglycemia of at least 1 year duration, HgbA1c level between 5.7-6.5% (39 to 48 mmol/mol), without any medic...
a single intravenous injection of Cy5.5, Cy5.5-SANPs, or Cy5.5-CNPs (Cy5.5 equiv.) The fluorescence intensity in the kidneys ofNpsh2-Cre+/Itgavfl/flmice was lower than that in the kidneys ofthe Itgavfl/flmice. Three days after intravenous injection of fTAC, SANPs, or CNPs (once a ...
patients might not able to maintain a good level of adherence to the insulin medication. As a step to improve the adherence level among diabetics, we would like to propose a reminder system that can promote a change in the patients’ behavior. This paper is divided into two scopes: the fir...
Pentobarbital (50 mg/kg, intraperitoneal injection) was used for euthanasia. The methods and results were reported in accordance with the in vivo animal experiment reporting requirements. Eight weeks later, the mice were euthanized, and the retina was removed and preserved in 4% paraformaldehyde for...