Antiseizure drugs,used to prevent epilepticseizures, can also relieve neuropathy. The drugs control the nerve cells in thebrainand other parts of your body, such as legs and arms, that transmit pain. But they can make you dizzy or sleepy, especially at high doses. ...
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Diabetic Neuropathies [drug therapy]FemaleFibromyalgia [drug therapy]HumaBackground Antiepileptic drugs have been used in pain management since the 1960s; some... L Hearn,S Derry,RA Moore - 《Cochrane Database of Systematic Reviews》 被引量: 55发表: 2012年 Methods of Managing Vascular Conditions...
including the seizure drugsgabapentinand valproate, antidepressants such as venlafaxine, duloxetine and amitriptyline and painkillers such asopioidsandcapsaicin. Transcutaneous electricnerve stimulation(TENS), a widely used pain therapy involving a portable device, was also found to be...
Nerve damage also makes it harder for you to feel pain or other symptoms of ulcers or infections. That can keep you from treating smaller wounds before they become ulcers. Ulcers are dangerous because they can lead to serious infections or even gangrene, which is when your tissue dies. In ...
The rapid effect of these drugs suggests a peripheral rather than central mode of action.A.J.M. Boulton and J.D. WardClinics in Endocrinology and MetabolismBoutton AJM,Ward JD.Diabetic neuropathies and pain. Journal of Clinical Endocrinology and Metabolism . 1986...
1 DPN may or may not be accompanied by chronic or episodic pain localized in the feet. It is a complex disorder in which the disease may affect different sets of nerve fibres to different degrees in different individuals.2 Thus, one individual may have an abnormality of large fibre sensory ...
changes occurring during the aging process may account for the facilitating effect of age on diabetic neuropathy. These include an increase in the production of advanced glycosylation end-products (AGEs), a defect in the polyol pathway, nerve vascular alterations and impaired resistance to oxidative ...
If you have nerve pain or peripheral neuropathy due to diabetes there is some evidence exercise may either improve or worsen nerve damage. Consequently, people with diabetes should always speak with their doctors to see which exercise program might be the best for them to participate in. People ...
TENS is a non-invasive treatment which applies an electrical current to nerve fibres through electrodes on the skin.65 It is theorised that a reduction in pain may be due to endogenous opioid release, gate control theory, and dilation of blood vessels.66 TENS ha...