Diabetic kidney disease: a report from an ADA consensus conference Diabetes Care, 37 (2014), pp. 2864-2883 CrossrefView in ScopusGoogle Scholar 12 G.H. Tesch, A.K.H. Lim Recent insights into diabetic renal injury from the db/db mouse model of type 2 diabetic nephropathy Am. J. Physiol...
Clinically, it has been observed that episodes of acute kidney injury (AKI) in individuals with DM are associated with an increased cumulative probability of progressing to end-stage chronic kidney disease [184]. In a recent study, the development of DM was initiated by the implementation of ...
Zhang K,Zhang Y,Yin SJ,et al. Recent advances of complement in kidney disease[J]. J Clin Nephrol,2022,22(4):339-343. DOI:10.3969/j.issn.1671-2390.2022.04.013. [16] Tan SM,Ziemann M,Thallas-Bonke V,et al. Complement C5a induces renal injury in diabetic kidney disease by disrupting...
Diabetic kidney disease (DKD) represents a significant public health burden, with a multifactorial link between chronic kidney disease (CKD), diabetes, and cardiovascular disease (CVD). Diabetic kidney disease (DKD) is the most common cause of CKD, often with comorbid hypertension, portending ...
Diabetic kidney disease (DKD) is the most common cause of chronic kidney disease in the United States. In the last several years, there have been several new developments in the field of the DKD. In 2007, the National Kidney Foundation and Kidney Disease Outcomes Quality Initiative released cli...
Indeed, recent findings have changed our overall concept of DN, reflected in the newer term of ‘Diabetic Kidney Disease’ (DKD) [8]. As a result of emerging evidence supporting a role for tubular involvement in DKD, interest has shifted to the proximal tubule (PT), which may play a role...
In the present review, we discussed the recent advances in cell-based therapy of diabetes, from foundational islet transplantation to regenerative strategies to highlight key developments that improve the effective treatments for diabetic patients. Cell replacement therapy for diabetes Pancreatic ...
Fig. 1.Pathways involved in the development of diabetic kidney disease. View article Diabetes Part 2 of 2 StephenThomas, inMedicine, 2010 Abstract Diabetic nephropathyis a major cause of morbidity and mortality in both type 1 andtype 2 diabetes. This is principally fromcoronary arteryand other ...
Genome-Wide Association Studies More recent technologic advances have revolutionized the field toward the second hypothesis-free generating approach, GWASs, in which up to millions of SNPs can be tested against traits such as DR. These developments include microarray-based technology with tag SNPs, us...
outcomes for patients is a key priority at Kidney Research UK. This work is an important step that will allow new treatments for diabetic kidney disease to be identified faster. We congratulate Simon and Matt on this innovative approach and look forward to seeing further developments from their ...