KetosisPediatricDiabetic ketoacidosis (DKA), a life-threatening complication of diabetes mellitus (DM), occurs more commonly in children with type 1 DM than type 2 DM. Hyperglycemia, metabolic acidosis, ketonemia, dehydration and various electrolyte abnormalities result from a relative or absolute ...
ELECTROLYTE BALANCE IN UNCONTROLLED AND CONTROLLED DIABETIC KETOSIS AND ACIDOSIS Soon after the discovery of insulin, Harrop and Benedict (1), and shortly thereafter Briggs and co-workers (2), demonstrated a fall in the potassium level in the plasma when insulin was administered. In the early per...
Management goals Treatment of ketoacidosis should aim for the following: Fluid resuscitation Reversal of the acidosis and ketosis Reduction in the plasma glucose concentration to normal Replenishment of electrolyte and volume losses Identification the underlying cause Pharmacotherapy Regular and analog ...
management is imperative and must continue concurrently. When blood glucose levels drop to below 14 mmol/l aglucose infusionshould be started. This enables insulin therapy to continue without hypoglycaemia, until ketosis has resolved. An example regime for the treatment of DKA is outlined inBox 2.2...
Fluid management in diabetic-acidosis - Ringer’s lactate versus normal saline: a randomized controlled trial. QJM 105, 337–343 (2012). Article PubMed CAS Google Scholar Kamel, K. S., Schreiber, M., Carlotti, A. P. & Halperin, M. L. Approach to the treatment of diabetic ...
Trever RW, Cluff LE: The problem of increasing azotemia during management of diabetic acidosis.Am J Med24:368–375, 1958. ArticlePubMedCASGoogle Scholar Linton AL, Kennedy AC: Diabetic ketosis complicated by acute renal failure.Postgrad Med J39:364–366, 1963. ...
In response to this imbalance, normal physiologic mechanisms are exaggerated, resulting in hyperglycemia, hyperosmolality, ketosis, and acidosis. (1) The biochemical criteria for the diagnosis of DKA are hyperglycemia (blood glucose level >200 mg/dL [>11.1 mmol/L]), venous pH less than 7.3 or...
Our study raises the question of whether ketosis may also play a role in these deaths. Children with long-standing diabetes but without DKA have been shown to have a longer QTc and a greater frequency of other abnormalities in cardiac autonomic function compared with age-matched control subjects...
We aimed to determine the nature of diabetic ketosis decompensations as well as the profile of kalemia and factors associated with its disorders at diagnosis of acidosis compared to non-acidosis diabetic ketosis. Methods: The study was retrospective from 1 January 2010 to 31 December 2011 in Yal...
The management of even preschool children with insulin pump therapy was not associated with an increased frequency or an accelerated rate of development of ketosis (Flores et al., 1984; Brambilla et al., 1987). However, Marshall et al. (1987) reported more abscesses and ketoacidosis in ...