Ketones/ketoacids/hydroxy acids, in particular, beta-hydroxybutyrate, induce nausea and vomiting that consequently aggravate fluid and electrolyte loss already existing in DKA. Moreover, acetone produces the fruity breath odor that is characteristic of ketotic patients. ...
The priorities for the management of Diabetic Ketoacidosis (DKA) are to assess severity and establish intravenous (i.v.) 0.9% NaCl rehydration with the careful addition of potassium ([K+]). Ideally, a fixed rate insulin infusion should be used initially and addition of 10% glucose infusion ...
Point-of-care beta-hydroxybutyrate testing for assessing diabetic ketoacidosis severity prior to treatment in the emergency department[J]. Diabetes Res Clin Pract, 2011, 96(3): e86-e88. 6 Laeger T, Cornelia C,Metge S, et al. Role of beta-hydroxybutyric acid in the central regulation of ...
Diabetic ketoacidosis (DKA) is a form of a hyperglycemic emergency mainly characterized by the triad of hyperglycemia, ketosis, and anion gap metabolic acidosis. DKA may be the initial presentation in approximately 25-40 % of patients with type 1 diabetes. It may also occur in at least 34% ...
Diabetic Ketoacidosis in the Pediatric ICU 2008, Pediatric Clinics of North America Citation Excerpt : Nonenzymatic decarboxylation of acetoacetate produces elevated acetone concentrations in plasma. Typically in DKA the ratio of beta-hydroxybutyrate to acetoacetate is about 3:1, but it may range up to...
1. Introduction People still die from diabetic ketoacidosis. Poor patient education is probably the most important determinant of the incidence of the catastrophe that constitutes "DKA". In several series, only about a fifth of patients with DKA are first-time presenters with recently acquired Type...
Bedside monitoring of blood beta-hydroxybutyrate levels in the management of diabetic ketoacidosis in children. Diabetic ketoacidosis (DKA) affects many children with type 1 diabetes. Insulin treatment of DKA is traditionally guided by changes in the blood glucose le... A Rewers,K Mcfann,HP Chase...
Distribution of 3-oxoacid CoA-transferase and 3-hydroxybutyrate dehydrogenase along the mouse nephron. Hoppe Seylers Z. Physiol. Chem. 364, 1727–1737 (1983). Article CAS PubMed Google Scholar Charfen, M. A. & Fernandez-Frackelton, M. Diabetic ketoacidosis. Emerg. Med. Clin. North Am. ...
diabetic ketoacidosis and hyperglycemic hyperosmolar nonketotic syndrome. Enhance your understanding ofnursing assessment, interventions, goals, andnursing diagnosis, all specifically tailored to address the unique needs of individuals with diabetic ketoacidosis and hyperglycemic hyperosmolar nonketotic syndrome...
3 Point-of-Care Beta-Hydroxybutyrate Testing for Assessing Diabetic Ketoacidosis Severity Prior to Treatment in the Emergency Department We prospectively evaluated the correlation between point-of-care β-OHB values and DKA severity at time of initial diagnosis in 54 patients. The correlatio... S ...