All 24 eyes in the DME group were treated with intravitreal ranibizumab (IVR) injections thrice monthly. The total number of injections was 3.09 ± 0.34 and 0 in the DME and NDME groups, respectively (P < 0.001). Baseline BCVA was log MAR 0.69 ± 0.09 in the DME group...
Thus, after reinitiation of ranibizumab injections, a minimum of two successive monthly treatments were required. Laser arm Patients received active laser photocoagulation on Day 1 (with option to split into two sessions with maximum of 4-week interval in between), and sham ranibizumab injection on...
Patients with a fluid-free macula at month 3 continued on ranibizumab 0.5-mg through month 12, wherein treatment was administered on an as-needed basis for recurrent DME documented on SD-OCT (Figure 1). At each monthly study visit, standardized visual acuity, SD-OCT, and a complete ...