It was not until 1955 when Shwachman provided the first description of diabetes associated with CF in three children2. Cystic fibrosis related diabetes (CFRD) was thought to be very rare in the past, but with the increasing longevity of CF patients this complication has become increasingly common...
Diabetes in Cystic Fibrosis 来自 NCBI 喜欢 0 阅读量: 19 作者: T Pfeifer 摘要: The article informs that cystic fibrosis (CF) is the most common lethal genetic disorder in the white population, with an incidence of approximately 1:2,500. The primary defect appears to be an abnormal chloride...
Islet amyloid was not present in any of the control cases. Islet amyloidosis derived from islet amyloid polypeptide is a characteristic feature of diabetes mellitus in CF as well as type II diabetes mellitus. 展开 关键词: Islets of Langerhans Humans Pancreatic Diseases Cystic Fibrosis Amyloidosis ...
Cystic fibrosis is the most commonly inherited life-threatening disease of Caucasians, with an incidence of 1 case per 3000 live births in the United States.16 The primary gene defect located on chromosome 7 was discovered in 1989. Since then, multiple mutations at this locus have been identifie...
Genomics and individuals in public health practice: are we luddites or can we meet the challenge? The complexity of biology is such that, even for inherited disorders such as thalassemia or cystic fibrosis, there is variation in the phenotype which in... Zimmern,L R. - 《Journal of Public ...
摘要 Importance of the field: Cystic fibrosis-related diabetes (CFRD) is a unique type of diabetes. In this article I reviewthe pathophysiology of CFRD to gain insight as to why these patients have clinical features of both type 1 and 2 diabetes (DM). The reader will also learn that, alt...
Cystic fibrosis-related diabetes (CFRD) is the principal extra-pulmonary complication of cystic fibrosis, occurring in 15-30% of adult cystic fibrosis patients. The number of cystic fibrosis patients who develop diabetes is increasing in parallel with increases in life expectancy. The aim of this ...
OBJECTIVE—Although cystic fibrosis–related diabetes (CFRD) is associated with decreased lung function, sex is not known to influence CFRD. However, compa... EJ Sims,MW Green,A Mehta - 《Diabetes Care》 被引量: 148发表: 2005年 Nutritional decline in cystic fibrosis related diabetes: The effec...
The effect of insulin therapy on lung function and lung infections was studied in a retrospective case-control design in 18 diabetic cystic fibrosis (CF) patients; 18 non-diabetic CF patients, matched for sex, age and presence of chronic Pseudomonas aeruginosa lung infection, served as controls....
The Development and Characterization of Diabetes Mellitus in Cystic FibrosisPediatric Research publishes original papers, invited reviews, and commentaries on the etiologies of diseases of children and disorders of development, extending from molecular biology to epidemiology. Use of model organisms and in ...