Researchers looked at over a quarter of a million children aged 6 to 18 and over a thousand children with type one diabetes who attended schools and colleges in Wales between 2009 and 2016. Factors such as the child’s household socioeconomic status, neighbourhood deprivation, sex and age were...
In Denmark, time trends of ischaemic stroke in people with type 2 diabetes are showing a striking decline. Between 1996 and 2015, the incidence of stroke dropped by around 50%. The fall coincided with an increase in the use of prophylactic cardiovascular medications, especially statins (where ...
Given the potential for teratogenicity, it is essential to ensure adequate contraception in sexually active females who are prescribed statins. Because of the amplified risk of cardiovascular disease in people with CKD (eGFR <...
The group-specific statin treatment patterns were similar for both sexes during the 6-year follow-up 2012–2017; however, women were overall and in all groups more often untreated and less frequently treated with high-intensity statins than men (Fig. 2). Figure 2 Annual statin treatment (%)...
When he stopped taking every one of his drugs with the support of his doctor, this man began following a low-carb diet and lost more than 35 pounds and his A1C dropped from 6.9 to 6.2. “Despite eating more eggs and lots of full fat Greek yoghurt, and stopping statins” his LDL chole...
Meta-analysis has shown that statins are the most effective therapy for reducing CV mortality, followed by PCSK9 inhibitors and statins in combination with ezetimibe. PCSK9 inhibitors effectively reduce MACEs [105], and statin therapy and add-on treatment with PCSK9 inhibitors or ezetimibe exhibit...
(P for interaction 0.005), had a baseline HbA1c level ≤9% (75 mmol/mol) (P for interaction 0.010) and ever used statins to control blood lipid (P for interaction 0.044); and was attenuated among patients who ever took antiplatelet drugs (P for interaction 0.003), as shown in the ...
medication review with replacement of potentially harmfulmedications such as ACE inhibitors, ARBs, statins and glucose-lowering drugs other thanmetformin and insulin. Immediate referral to specialist antenatal care as soon as pregnancy isconfirmed is also recommended. The NPID report recommends ...
Statins and platelet aggregation inhibitors can be used to lower the risk of CV events. For patients with CKD associated with T2D, regulation of blood glucose is important. Blood glucose-lowering treatments include metformin, sulfonylurea, sodium-glucose cotransporter-2 (SGLT2) inhibitors, glucagon-...
Liver safety of statins in prediabetes or T2DM and nonalcoholic steatohepatitis: post-hoc analysis of a randomized trial. J. Clin. Endocrinol. Metab. 102, 2950–2961 (2017). Article PubMed PubMed Central Google Scholar Friedman, S. L. et al. A randomized, placebo-controlled trial of ...