In just two years, people with type 2 diabetes experienced negative changes in their ability to regulate blood flow in the brain, which was associated with lower scores on tests of cognition skills and their ability to perform their daily activities, according to a new study published in the J...
Long Term effect of a structured inpatient diabetes teaching and treatment programme in type 2 diabetic patients: influence of mode of follow-up. Diabetes Res Clin Pract 1999;46(2):135.Fritsche A, Stumvoll M, Goebbel S, Reinauer KM, Schmulling RM, Haring HU. Long term effects of a ...
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med. 2002;346(6):393-403. doi:10.1056/NEJMoa012512PubMedGoogle Scholar 19. Diabetes Prevention Program Research Group. Long-term effects of metformin on diabetes prevention: identification of ...
Efficacy and Tolerability of Exenatide Once Weekly Over 6 Years in Patients with Type 2 Diabetes: An Uncontrolled Open-Label Extension of the DURATION-1 Study Long-term treatment is necessary to slow the progression of type 2 diabetes (T2D). Here, we examined the safety and efficacy of 6 yea...
Some types of diabetes are temporary or reversible, like gestational diabetes. Other types are long term and permanent, like Type 1 and Type 2 diabetes. The different types of diabetes are more like a spectrum, rather than distinct categories. And people can have more than one type of diabete...
This study aims to assess the effects of a community-based lifestyle intervention program on the incidence of type 2 diabetes (T2D). For this purpose, three communities in Tehran were chosen; one community received a face-to-face educational session embedded in a long-term community-wide life...
Insulin secretion adapts to metabolic needs, but how this happens over the short term is not clear. Here the authors show this involves upregulation of beta-cell exocytosis and requires the SUMO-protease SENP1, which responds to redox state in a zinc-dependent manner. ...
In conclusion, the present study shows that long-term PE treatment in obese SHR/N-cp rats with NIDDM and hypertension effectively controlled systemic arterial pressure and resulted in a significant reduction in left ventricular weight. However, these favorable effects of PE were not associated with ...
Short- and long-term effects of real-time medication monitoring with short message service (SMS) reminders for missed doses on the refill adherence of peop... Short- and long-term effects of real-time medication monitoring with short message service (SMS) reminders for missed doses on the re...
In the future, expansion with longitudinal multi-omics data and modeling time could add more information on the causality of the drugs by investigating the long-term effects and associations32. Similarly, our approach opens up for individualized analysis of patients in an N-of-1 approach61. It ...