大 鼠在空间辨别性学 习记忆时海马 CA1 ,CA3 区和 DG 的 ACh 能纤维 和星形胶质细胞的变化 225参照 张 秀池设计[3】 的水迷 宫,用透 明聚 乙 烯有 机玻 璃制作 ,长、 宽各 100cm ,高30cm ,泳路宽 12cm ,正 确泳路长220cm.水深25cm ,水温 (23 ± 1)℃. 每一 个训 练 日结 束后,清洗...
图像分析仪对大鼠海马CA1,CA3区及DG的GR免疫阳性星形胶质 细胞的数量及其GFAP表达进行检测. 结果模型组与对照组相比大鼠各观察部位的AChE阳性纤维的密度 和含量均增高,有显着性差异(P<0.05). 而空白组和游水组相比大鼠各观察部位的AChE阳性纤维的密度和 ...
通常简化为CA1和CA3两部分.锥体细胞(P., pyramidalcell)是海马CA3的主要成分,它们之间 通过抑制性中间神经元(I.,interneuron)相连接. CA3锥体细胞的自然发放产生兴奋性的突触后电位 (excitatorypostsynapticpotentials).随着人们对大 脑记忆系统兴趣不断增加,对海马结构的研究也逐 ...
Moreover, selective chemogenetic inactivation of DG–CA3 circuitry completely and reversibly abolishes the CA1 representation of latent information. These results reveal a causal and specific role of DG–CA3 circuitry in the maintenance of latent information within the hippocampus....
These results suggest that the DG/CA3 is the core region for pattern separation during the encoding phase and interacts with the medial CA1, depending on the similarity of the stimuli, to achieve effective encoding. Impaired activity in the DG/CA3, as well as in the lateral CA1, was found...
1FK7100-2AF71-1RH1 1FK7103-2AC71-1RG1 1FK7103-2AC71-1RH1 1FT7046-5AF70-1CA0 1FK7042-5AF71-1AA0 1FK7042-5AF71-1AG0 1FK7042-5AF71-1AH0 1FK7042-5AF71-1DG5 1FK7042-5AF71-1EG0 1FK7042-5AF71-1EH0 1FK7042-5AF71-1SA0 1FK7042-5AF71-1SG0 1FK7042-5AF71-1UA0 ...
本研究显示,电针百会和大椎穴对癫痫大鼠具有一定的疗效,并与CA3和DG区GAD67表达水平的变化有关。 引用本文: 高东升,杨晓燕,马临庆,等.电针对癫痫模型大鼠自发性反复发作及海马CA3和DG区谷氨酸脱羧酶67表达的影响[J].国际神经病学神经...
Toward the goal of better understanding the coding in the trisynaptic pathway from the dentate gyrus (DG) to the CA3 and CA1, we report a novel microfabricated device that divides a micro-electrode array into two compartments of separate hippocampal network subregions connected by axons that grow...
Moreover, the CA1 and CA3 regions showed higher vulnerability, with signs of reactive astrogliosis such as increased astrocyte density and elevated GFAP expression. Additionally, we observed a significant rise in microglia density, along with elevated inflammatory markers (TNF伪) in these hippocampal ...
6SN1124-1AA00-0EA2功率模块 6SN1127-2ED10-0HA0 6SN1161-1CA00-0AA1 驱动总线 6SN1161-1CA00-0EA1驱动总线 6SN1161-1CA00-0BA0驱动总线 6SN1161-1CA00-0AA0驱动总线 6SN1162-1AA00-0AA0通用空外壳 6SN1146-1BB00-0EA1馈电模块/回馈模块 6SN1123-1AB00-0AA2功率模块 6SN1123-1AB00-0CA3功...