DEXBORNEOL,来源于药化词典-药智数据
Edaravone dexborneol (EDB) is a new type of neuroprotective agent that can improve the neurological damage caused by an ischemic stroke. Previous studies showed that EDB has effects on synergistic antioxidants and induces anti-apoptotic responses. However, it remains unclear whether EDB can affect ...
et al. Edaravone Dexborneol mitigates pathology in animal and cell culture models of Alzheimer’s disease by inhibiting neuroinflammation and neuronal necroptosis. Cell Biosci 14, 55 (2024). https://doi.org/10.1186/s13578-024-01230-8 Download citation Received25 January 2024 Accepted05 April ...
Edaravone dexborneol alleviates pericyte-mediated fibrosis depositing extracellular matrix through TGF-β1/IL-11 in cerebral small vessel disease Qingrui Duan, Zhiyang Liu, Yuxuan Xing, Haifeng Huang, Lin Zhu, Jiaxuan Liu, Peikun He, Guixian Ma, Yuhu Zhang, Kun Nie, Yuyuan Gao...
D-BORNEOL [WHO-DD] D-CAMPHANOL DEXBORNEOL FEMA NO. 2157, (+)- CAS登记号464-43-7 物质唯一标识(Unique Ingredient Identifier)8D24LWT4FK 分子式C10H18O 国际化合物标识(International Chemical Identifier,InChI)DTGKSKDOIYIVQL-WEDXCCLWSA-N
This randomized clinical trial investigates if sublingual edaravone dexborneol improves functional outcome in patients with acute ischemic stroke.
Edaravone dexborneol Ischemic stroke Neuroinflammation Microglia/macrophages Leukocyte infiltration Peripheral inflammation 1. Introduction Stroke is a complex cerebrovascular disease caused by the disruption of cerebral vessels or regional interruption of blood flow to the cerebral tissue due to thrombosis or ...
For the secondary outcomes, an ordinal comparison of the distribution of patients across mRS categories showed that the good function outcome favored the edaravone dexborneol group (common OR, 1.33; 95% CI, 1.05-1.68). Despite this, edaravone dexborneol had no impact on other prespe...
Keywords: cerebral ischemia reperfusion injury,edaravone dexborneol,inflammation,nadph oxidase 2,nrf2/ho‐1 pathway Data availability: Keywords: cerebral ischemia reperfusion injury, edaravone dexborneol, inflammation, nadph oxidase 2, nrf2/ho‐1 pathway ...
Safety and efficacy of Edaravone Dexborneol versus edaravone for patients with acute ischaemic stroke: a phase II, multicentre, randomised, double-blind, multiple-dose, active-controlled clinical trialSafety and efficacy of Edaravone Dexborneol versus edaravone for patients with acute ischaemic stroke: ...