The present invention discloses a dexamethasone palmitate liposome injection preparation method, the liposome injection by a specific weight ratio of dexamethasone palmitate, cetyl two phospholipids, cholesterol, Tween 80, made from glucose and dextran. 本发明的脂质体注射液具有良好的制剂稳定性,冷冻过程中...
Dexamethasone-21-palmitate in lipid microspheres has already demonstrated its efficacy and tolerability with intra-articular injection during the inflammatory phase of osteoarthritis of the knee[6]and following periarticular administration in acute radial epicondylitis of the humerus.[7]The results of the ...
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Intravitreal injectionRetinal diseaseTiny nanoparticles of dexamethasone palmitate (DXP) were designed as transparent suspensions for intravitreal administration to treat age-related macular degeneration (AMD). The influence of three surfactants (PEG-40-stearate and Pluronic block copolymers F68 and F127) ...
deoxythymidinepalmitate, an antiHIVprodrug, was encapsulated in PEG-modified SLN[104], and its biodistribution was studied by intravenous injection to CD-1 mice. The results suggest that there was an increase in bioavailability by encapsulation of 3′-azido-3′-deoxythymidine palmitate in SLN. SLN...
[47,48]. Furthermore, it has been reported that MET abolished palmitate-induced lipotoxicity and hepatic apoptosis [49]. Most recently, MET has been shown to attenuate hepatic steatosis by autophagy and necroptosis modulation [50]. Supporting these notions, MET successfully diminished DEXA-induced ...
No patients in the combination therapy group required an NSAID after the injection. According to patient-assessed effects on quality of life, very clear benefits with dexamethasone palmitate therapy were present at the end of the observation period. Before the start of therapy, 58% of dexamethasone...
Dexamethasone injection. ... The drug is indicated: (A) For the treatment of primary bovine ketosis and as an anti-inflammatory agent in cattle and horses; (B) As an anti-inflammatory agent in dogs and cats. ... Federal law restricts this drug to use by or on the order of a ...
studyinvolvingtheinjectionofdexamethasonepalmitatetohealthyvolunteers. ©2007ElsevierB.V.Allrightsreserved. Keywords:Dexamethasone;Dexamethasonepalmitate;LC/MS/MS;Pharmacokinetics;Human 1.Introduction Dexamethasoneisapotentanti-inflammatorysteroidwidely usedfortreatinginflammatoryconditions,allergicreactions, shockan...
& Mao, N. In vitro and in vivo studies on ocular vitamin A palmitate cationic liposomal in situ gels. Int. J. Pharm. 458, 305–314 (2013). Article CAS PubMed Google Scholar Liao, J. & Huang, H. A fungal chitin derived from Hericium erinaceus residue: Dissolution, gelation and ...