The staging of human embryos, as distinct from seriation, depends on a morphological scheme devised by Streeter and completed by O’Rahilly, who proposed the term Carnegie stages. To avoid misconceptions and errors, and to place new findings in perspective, it is necessary to summarize th...
3c,d). Strikingly, embryos identified to be abnormal by a human scientist frequently deviated from this normal range much earlier (Fig. 3c,d). Based on low average similarity values, abnormally developing embryos could be detected in a batch of sibling embryos at early stages (Fig. 3c). It...
Developmental stages in the human thymus - Res, Spits - 1999 () Citation Context ...; Kutlesˇa et al., 2002). Defined stages of thymocyte development within the thymic lobules can be monitored by the expression of accessory molecules, for example, CD4 and CD8 (Shortman and Wu, 1996; ...
similarly derived from the pre-implantation stages of IVF-derived morula or blastocyst-staged human embryos, they are phenotypically similar in culture with post-implantation primed murine epiblast stem cells (mEpiSC; blue). A primed, mEpiSC-like state of pluripotency is also attained through the e...
The Culture of Schistosoma mansoni and Production of Life Cycle Stages Schistosoma mansoni is a trematode parasite with a freshwater snail intermediate host but whose definitive host is human. Schistosomiasis is a chronically debilitating, and often fatal disease affecti F Hackett - 《Methods Mol Bio...
For all three stages, 25 kHz was either optimal or near-optimal for monitoring and quantifying schistosome motility. These improvements in methodology sensitivity should enhance the capacity to screen small compound libraries for new drugs both for schistosomes and other helminth pathogens at large. ...
published in his 1950 bookChildhoodand Society—and expanded and refined in later books, notablyIdentityand the Life Cycle—Erikson’s framework emphasizes the impact of family and social interactions on emotional development across eight stages that traverse the entire lifespan, from infancy to ol...
also present in at least one of the other three normalization methods (Fig.1B). Figure 1 Transcriptome-wide analysis of the stability of candidate reference genes for quantitative RT-PCR assays across six life-cycle stages ofS. mansoni. Twenty-four RNA-Seq libraries comprising sixS. mansonilife...
Anin vivogain-of-function reporter fly line can sensitively detect translational readthrough We wished to measure stop codon readthrough in flies across developmental stages of their life cycle. We initially chose to measure readthrough using a candidate gene,rab6, which had been identified as und...
Gene expression profiles were linked to the major environmental settings through which the developmental stages of the fluke have to adapt during the course of its life cycle. Gene ontologies of the differentially expressed genes revealed a wide range of functions and processes. In addition, stage-...