Individuals in the non-spectrum profile show non-spectrum symptom severity in both the SA and RRB domains. Individuals in the RRB and SA profiles show ASD symptoms on the autism spectrum level in the SA and RRB domains, respectively, while scoring within the normal range in the other domain....
From worms to humans, the nervous system undergoes extensive transcriptional and functional transformation upon sexual maturation18,21,54. We thus searched specifically for neuronal gene families that display sexually dimorphic expression in our dataset. We examined transcription factor families55, including ...
Anxiety was measured using the DSM-oriented scale on anxiety problems of the youth self-report (YSR) of the ASEBA [16]. Youth rated all YSR items on a 3-point Likert scale from 0 (Not true) to 2 (Very true or often true). The YSR was used because past research has found that you...
social communication difficulties To provide an absolute measure of shared genetic influences between traits and clinically recognised conditions, we assessed the phenotypic variance in rank-transformed social communica- tion difficulties due to risk-increasing alleles using polygenic scoring43,44 (Table 1)...
Individuals scoring high on this personality dimension can be characterized as worried, emotionally unstable, overly reactive or nervous [5]. Particularly, the association between high neuroticism and internalizing disorders like depression [6],[7] or anxiety disorders [8],[9] is well established. ...
Aging affects epidermal Langerhans cell development and function and alters their miRNA gene expression profile Aging (Albany N.Y.), 4 (2012), pp. 742-754 Google Scholar Yoshiki et al., 2014 R. Yoshiki, K. Kabashima, T. Honda, S. Nakamizo, Y. Sawada, K. Sugita, H. Yoshioka, S. ...
Notably, in our study, children with 22q11DS also scored lower on the PPVT than children with DLD, with most DLD children scoring within the normal (or even above-normal in two cases) range, whereas most 22q11DS children scored below average on the PPVT. Our post-hoc analysis on the ...
(i.e., training and supervision of researchers processing and scoring of data). Administration of the WPPSI-III, CELF-Preschool and PPVT-III was performed seated on a table by trained child psychologists in the Dutch or English language, depending on the first language of the child. The SRS...
each autistic individual has their own unique profile of strengths and challenges, which may influence not only a person’s experience of well-being, but also their definition of what constitutes their specific well-being. Furthermore, many autistic people are reported to have co-occurring conditio...
Despite the fact that children can draw on their memories to make novel inferences, it is unknown whether they do so through the same neural mechanisms as adults. We measured memory reinstatement as participants aged 7–30 years learned new, related info