Pediatrics Department, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, 3333 Burnet Ave, MLC 4002, Cincinnati, OH, United States. Rebecca.shaffer@cchmc.org.Jessica.HellingsUniversity of Missouri-Kansas City, University Health Behavioral Health, Kansas City, MO...
De novo mutations and copy number deletions inNRXN1(2p16.3) pose a significant risk for schizophrenia (SCZ). It is unclear howNRXN1deletions impact cortical development in a cell type-specific manner and disease background modulates these phenotypes. Here, we leveraged human pluripotent stem cell-...