Most of the differences between inorganic, organic, and protein crystals lies in the fact that ionic forces (found mostly in inorganic structures) depend upon interatomic distances but not on angle. In contrast, covalent bonds (such as those which predominate in organic and protein compounds) ...
which effects temporary or permanent immobilization, fixation or adhesion of the probe nucleotide to a site or in a region of the carrier; for example, by the formation of covalent, ionic, metallo-organic bonds, binding based on van der Waal's forces, or enzyme substrate interactions or ...
The NBO and DOS analyses have shown that the stability of the TMMg30, clusters is governed by the charge transfer processes as well as the nature of interaction of the atomic orbitals. These studies also confirm that the neutral doped clusters exhibit covalent-like bonding...
If immobilized, the bioconcentrator may be immobilized by any of a wide variety of mechanisms as are known by those versed in the art, including, for example, adsorption, cross-linking, adsorption coupled with cross-linking, covalent bonding, entrapment, etc., and may be immobilized on a surf...
We have also undertaken a parallel study of 24 acrylamide-based covalent reactive groups (CRGs) and have likewise included these species in a global analysis for all 89 small molecule drug candidates. We demonstrate that, with the aid of supervised machine learning (ML), the full range of DMS...
temperature, pH, and ionic strength, resulting in the continuous presence of transitional intermediates (37). However, a favored conformation governed by environmental conditions may represent the bulk of the protein population. The analysis of protein CSD patterns in ESI spectra is generally considered...
The following models were used to characterize the bonds between the oxygen atoms of the polymer chain with the different metals; theory of non-covalent interactions (NCI), natural bonding orbitals (NBO) method, and topological analysis of the electronic location function (ELF). Our results showed...
Krishnan-Ghosh, Y., et al., “Dynamic Covalent Chemistry on Self-Templating Peptides: Formation of a Disulfide-Linked Beta-Hairpin Mimic”, Angew. Chem. Int. Ed., May 16, 2003, vol. 42(19), pp. 2171-2173. Leung, K.H., et al., “Dynamic RNA Nanotechnology Enters the CRISPR Tool...
For example, direct joining may be via a covalent linkage, chelation or ionic interaction. Indirect joining occurs when the immobilized probe is joined to the solid support by one or more linkers. A “linker” is a means for binding at least two different molecules into a stable complex and...